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Cyclic AMP (CID 6076) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(11)
 
 
Inactive(7)
 
 
Unspecified(38)
 
 
Top Targets:
ABCC MRP doma..(10)
 
 
CAP ED(5)
 
 
 
MFS(3)
 
 
STKc PKA(2)
 
 
alcohol DH cl..(2)
 
 
BioAssay Types:
Literature(56)
 
 
 
 
BioActivity Types:
Potency(3)
 
 
IC50(2)
 
 
Ki(2)
 
 
EC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 51    Data Row: 56   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103317043]
Km 0.05Inhibition of Phosphodiesterase 8 [AID158285, Type: Literature]CAMP-specific cyclic nucleotide phosphodiesterase PDE8 [gi:81864950]
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2
[SID103317043]
Km 0.2Inhibition of Phosphodiesterase 7 [AID158280, Type: Literature]
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3
[SID103317043]
Km 0.53Affinity for bovine heart phosphodiesterase [AID158420, Type: Literature]
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4
[SID103317043]
Km 0.56Affinity for rabbit lung phosphodiesterase [AID158735, Type: Literature]
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5
[SID103317043]
Km 0.56Inhibition of rabbit lung cAMP Phosphodiesterase [AID219819, Type: Literature]
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6
[SID103317043]
Km 0.71Activity of bovine aortic PDE4 [AID628762, Type: Literature]
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7
[SID103317043]
Km 0.79Affinity for rabbit kidney phosphodiesterase [AID158734, Type: Literature]
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8
[SID103317043]
Km 1.3Inhibition of bovine brain cAMP Phosphodiesterase [AID219691, Type: Literature]
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9
[SID103317043]
IC50 40Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay [AID723507, Type: Literature]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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10
[SID103317043]
IC50 48Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis [AID663168, Type: Literature]
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11
[SID103317043]
Activation of olfactory CNG A2A41b channel expressed in HEK293 cells assessed as effect on half maximal current [AID297178, Type: Literature]
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12
[SID103317043]
EC50 1GRAC: human CNGA2 activator [AID540671, Type: Literature]Cyclic nucleotide-gated olfactory channel [gi:119370323]
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13
[SID103317043]
Km 44.5TP_TRANSPORTER: uptake in membrane vesicles from MRP4-expressing Sf9 cells [AID679496, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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14
[SID103317043]
Km 150Inhibition of Phosphodiesterase 5 [AID158111, Type: Literature]cGMP-specific 3',5'-cyclic phosphodiesterase [gi:5921804]
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15
[SID103317043]
Km 379TP_TRANSPORTER: uptake in membrane vesicles from MRP5-expressing V79 cells [AID680352, Type: Literature]Multidrug resistance-associated protein 5 [gi:8928547]
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16
[SID103317043]
Ki 780Inhibition constant was evaluated against horse liver alcohol dehydrogenase [AID33710, Type: Literature]Alcohol dehydrogenase S chain [gi:113406]
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17
[SID103317043]
Ki 780Inhibition constant was evaluated against horse liver alcohol dehydrogenase [AID33710, Type: Literature]Alcohol dehydrogenase E chain [gi:113397]
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18
[SID103317043]
ED50 5000Antiviral activity against Herpes simplex virus -2 strain MS was evaluated in african green monkey kidney [AID84938, Type: Literature]
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19
[SID103317043]
ED50 5000Antiviral activity against Herpes simplex virus -1 strain KOS was evaluated in african green monkey kidney [AID86027, Type: Literature]
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20
[SID103317043]
ED50 5000Antiviral activity against Para influenza virus type 3 strain C243 was evaluated in african green monkey kidney [AID155571, Type: Literature]
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