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Hydrocodone (CID 5284569) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(5)
 
 
Inactive(58)
 
 
Inconclusive(10)
 
 
Unspecified(18)
 
 
Top Targets:
p450(6)
 
 
7TM GPCR Srx(3)
 
 
 
BioAssay Types:
Literature(91)
 
 
 
 
 
BioActivity Types:
Ki(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 30    Data Row: 91   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103526751]
Ki 0.0095Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID670110, Type: Literature]Mu-type opioid receptor [gi:2851402]
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2
[SID103526751]
Ki 0.26Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID670111, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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3
[SID103526751]
ED50 2.4Analgesic activity was measured by acetic acid writhing test in mouse by giving subcutaneous injection [AID128495, Type: Literature]
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4
[SID103526751]
ED50 5.2Analgesic activity measured by rat tail flick assay following s.c. administration. [AID177776, Type: Literature]
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5
[SID103526751]
Metabolic stability in human liver microsomes assessed as GSH adduct formation at 100 uM after 90 mins by HPLC-MS analysis [AID678721, Type: Literature]
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6
[SID103526751]
Analgesic agonist activity in acetic acid induced mouse writhing assay, subcutaneous administration [AID131018, Type: Literature]
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7
[SID103526751]
The effective dose was measured by using mouse writhing assay after the compound administered subcutaneously. [AID132133, Type: Literature]
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8
[SID103526751]
Narcotic agonist activity using acetic acid induced writhing in the mouse upon subcutaneous administration [AID127831, Type: Literature]
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9
[SID103526751]
Compound was tested for analgesia in mouse writhing assay by subcutaneous administration [AID128023, Type: Literature]
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10
[SID103526751]
Compound was tested for analgesic activity by writhing assay in mouse after subcutaneous administration [AID128027, Type: Literature]
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11
[SID103526751]
Narcotic agonistic activity in acetic acid mouse writhing assay after subcutaneous administration of the drug [AID128214, Type: Literature]
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12
[SID103526751]
Agonistic activity by mouse acetic acid writhing test. [AID128307, Type: Literature]
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13
[SID103526751]
Displacement of [3H]-naltrindole from human delta opioid receptor expressed in CHO cells at 10 uM after 3 hrs by scintillation counting [AID670114, Type: Literature]Delta-type opioid receptor [gi:311033488]
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14
[SID103526751]
Selectivity index, ratio of inhibition of human delta opioid receptor to inhibition of human mu opioid receptor [AID670115, Type: Literature]
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15
[SID103526751]
Selectivity index, ratio of inhibition of human kappa opioid receptor to inhibition of human mu opioid receptor [AID670116, Type: Literature]
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16
[SID103526751]
Compound was tested for analgesic activity by tail-flick assay in rat after subcutaneous administration [AID178138, Type: Literature]
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17
[SID103526751]
Analgesic agonist activity in heat stimulus rat tail-flick assay on subcutaneous administration [AID178144, Type: Literature]
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18
[SID103526751]
Antagonist activity in rat tail flick assay by subcutaneous administration [AID178161, Type: Literature]
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19
[SID103526751]
Compound was tested for antinociceptive activity in heat stimulus rat tail flick assay after subcutaneous administration of the drug [AID178325, Type: Literature]
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20
[SID103526751]
Effective dose was measured by using rat tail flick assay after subcutaneous administration [AID180157, Type: Literature]
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