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Ibuprofen (CID 3672) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(96)
 
 
Inactive(100)
 
 
Inconclusive(19)
 
 
Unspecified(467)
 
 
Top Targets:
prostaglandin..(66)
 
 
 
 
GT1 Gtf like(12)
 
 
ALBUMIN(7)
 
 
 
Amidase(6)
 
 
 
p450(6)
 
 
BioAssay Types:
Literature(682)
 
 
 
 
 
BioActivity Types:
IC50(108)
 
 
 
 
 
Ki(6)
 
 
 
Potency(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 612    Data Row: 682   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103174500]
IC50 0.1Inhibition activity against recombinant human Prostaglandin G/H synthase 2 [AID162632, Type: Literature]
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2
[SID103174500]
IC50 0.22Inhibition of PGE-2 production in 3T3 (murine fibroblast) cell culture. [AID160863, Type: Literature]
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3
[SID103174500]
IC50 1.06Reverisible competitive inhibition of prostaglandin G/H synthase 1 [AID162150, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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4
[SID103174500]
IC50 1.1In vitro inhibitory concentration against COX-2 enzyme [AID240796, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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5
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID288822, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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6
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID344874, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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7
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immunoassay [AID352496, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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8
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID368229, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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9
[SID103174500]
IC50 1.1Inhibition of bovine COX2 by enzyme immunoassay [AID393820, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914301]
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10
[SID103174500]
IC50 1.1Inhibition of human recombinant COX-2 by enzyme immuno assay [AID443725, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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11
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID447529, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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12
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID457929, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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13
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID461113, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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14
[SID103174500]
IC50 1.1Inhibition of human COX2 by enzyme immunoassay [AID494635, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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15
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immuno assay [AID474248, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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16
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immuno assay [AID603429, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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17
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID622556, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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18
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID648862, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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19
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID724444, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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20
[SID103174500]
Ki 1.12202Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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21
[SID103174500]
IC50 1.35Inhibition of human COX2 expressed in baculovirus system [AID664057, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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22
[SID103174500]
IC50 1.4Inhibition of human recombinant COX-2 [AID587449, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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23
[SID103174500]
IC50 2Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell line [AID161005, Type: Literature]
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24
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID344873, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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25
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID368225, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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26
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID288821, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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27
[SID103174500]
IC50 2.9In vitro inhibitory concentration against COX-1 enzyme [AID240795, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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28
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID352495, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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29
[SID103174500]
IC50 2.9Inhibition of bovine COX1 by enzyme immunoassay [AID393818, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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30
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID474247, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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31
[SID103174500]
IC50 2.9Inhibition of sheep COX1 by enzyme immunoassay [AID494634, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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32
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID603428, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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33
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID622474, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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34
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID457928, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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35
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID461111, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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36
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID447528, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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37
[SID103174500]
IC50 2.9Inhibition of bovine COX-1 by enzyme immuno assay [AID443726, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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38
[SID103174500]
IC50 2.9Inhibition of ovine COX1 [AID648861, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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39
[SID103174500]
IC50 2.9Inhibition of ovine COX1 [AID724443, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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40
[SID103174500]
IC50 3Binding affinity to bovine serum albumin [AID323982, Type: Literature]Serum albumin [gi:1351907]
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41
[SID103174500]
IC50 3Inhibitory activity against prostaglandin G/H synthase 1 (COX-1) [AID161655, Type: Literature]
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42
[SID103174500]
IC50 3Concentration (in uM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50. [AID161679, Type: Literature]
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43
[SID103174500]
IC50 3Inhibition of Prostaglandin G/H synthase 1 (COX-1). [AID161680, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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44
[SID103174500]
IC50 4Inhibition of ovine COX-1 [AID587448, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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45
[SID103174500]
Ki 4.67735Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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46
[SID103174500]
IC50 5Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassay [AID701504, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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47
[SID103174500]
IC50 6.2Inhibition of COX2 in human whole blood after 15 mins [AID299910, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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48
[SID103174500]
IC50 6.9Inhibition of COX1 in human whole blood after 15 mins [AID299909, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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49
[SID103174500]
IC50 8Tested for inhibitory activity against Prostaglandin G/H synthase 2 from human [AID162666, Type: Literature]
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50
[SID103174500]
IC50 9Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovine [AID162151, Type: Literature]
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