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Acetic Acid (CID 176) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(6)
 
 
Inactive(11)
 
 
Unspecified(74)
 
 
Top Targets:
NT POLXc(2)
 
 
PolY Pol IV k..(2)
 
 
BioAssay Types:
Literature(91)
 
 
 
 
BioActivity Types:
Kd(2)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 91    Data Row: 91   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176092]
Kd 0.64Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase [AID224294, Type: Literature]
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2
[SID103176092]
Kd 0.9Dissociation constant for binding to SH2 domain of Fyn protein kinase [AID72281, Type: Literature]
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3
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in GFP-fused DAF16 transcription factor mRNA expression at 50 ppm by quantitative RT-PCR analysis [AID452647, Type: Literature]
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4
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in lifespan at 50 ppm by microscopic analysis [AID452626, Type: Literature]
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5
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in DAF16 transcription factor mRNA expression at 50 ppm after 2 days by quantitative RT-PCR analysis [AID452627, Type: Literature]
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6
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as decrease in DAF2 receptor mRNA expression at 50 ppm after 2 days by quantitative RT-PCR analysis [AID452628, Type: Literature]
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7
[SID103176092]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
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8
[SID103176092]
IC50 120Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production [AID454554, Type: Literature]Free fatty acid receptor 2 [gi:3122160]
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9
[SID103176092]
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production relative to acetate [AID454564, Type: Literature]Free fatty acid receptor 2 [gi:3122160]
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10
[SID103176092]
Toxicity in po dosed ICR mouse assessed as decreased in mobility after 3 hrs [AID498773, Type: Literature]
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11
[SID103176092]
Toxicity in po dosed mouse [AID498775, Type: Literature]
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12
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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13
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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14
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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15
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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16
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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17
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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18
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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19
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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20
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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21
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis [AID625285, Type: Literature]
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22
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis [AID625286, Type: Literature]
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23
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly [AID625287, Type: Literature]
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24
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice [AID625288, Type: Literature]
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25
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease [AID625289, Type: Literature]
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26
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty [AID625290, Type: Literature]
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27
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal [AID625291, Type: Literature]
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28
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score [AID625292, Type: Literature]
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29
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as survival time at 50 ppm by fluorescent microscopy [AID452648, Type: Literature]
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30
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in lifespan at 50 ppm by fluorescent microscopy relative to control [AID452649, Type: Literature]
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31
[SID103176092]
Cytotoxicity against mouse RAW264.7 cells at 5 uM [AID627980, Type: Literature]
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32
[SID103176092]
Affinity for Vancomycin (Exp I) [AID227555, Type: Literature]
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33
[SID103176092]
Affinity for Vancomycin (Exp II) [AID227556, Type: Literature]
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34
[SID103176092]
Binding energy by using the equation deltaG obsd = -RT ln KD [AID227718, Type: Literature]
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35
[SID103176092]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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36
[SID103176092]
Dissociation constant, pKa of the compound [AID342464, Type: Literature]
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37
[SID103176092]
Dissociation constant, pKa of the compound [AID448096, Type: Literature]
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38
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in lifespan at 50 ppm by microscopic analysis relative to control [AID452629, Type: Literature]
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39
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in lifespan at 50 ppm after 2 weeks by microscopic analysis relative to control [AID452630, Type: Literature]
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40
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of vit6 protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452631, Type: Literature]
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41
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of probable voltage-dependent anion-selective channel protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452632, Type: Literature]
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42
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of ATPA synthase subunit alpha, mitochondrial precursor protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452633, Type: Literature]
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43
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of aspartate aminotransferase protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452634, Type: Literature]
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44
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of nucleoside diphosphate kinase protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452635, Type: Literature]
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45
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of mlc3 protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452636, Type: Literature]
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46
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of mlc1 protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452637, Type: Literature]
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47
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of tropomyosin isoform A protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452638, Type: Literature]
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48
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of tropomyosin isoform B protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452639, Type: Literature]
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49
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of tropomyosin isoform D protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452640, Type: Literature]
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50
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as ratio of tropomyosin isoform F protein expression in stress to normal condition at 50 ppm after 3 days by second-dimensional electrophoresis/image analysis coupled with LC-MS/MS analysis [AID452641, Type: Literature]
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