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Acetic Acid (CID 176) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(6)
 
 
Inactive(11)
 
 
Unspecified(80)
 
 
Top Targets:
KAZAL SLC21(3)
 
 
NT POLXc(2)
 
 
PolY Pol IV k..(2)
 
 
MFS(1)
 
 
BioAssay Types:
Literature(97)
 
 
 
 
BioActivity Types:
Kd(2)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 97    Data Row: 97   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176092]
Kd 0.64Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinase [AID224294, Type: Literature]
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2
[SID103176092]
Kd 0.9Dissociation constant for binding to SH2 domain of Fyn protein kinase [AID72281, Type: Literature]
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3
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in GFP-fused DAF16 transcription factor mRNA expression at 50 ppm by quantitative RT-PCR analysis [AID452647, Type: Literature]
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4
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in lifespan at 50 ppm by microscopic analysis [AID452626, Type: Literature]
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5
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as increase in DAF16 transcription factor mRNA expression at 50 ppm after 2 days by quantitative RT-PCR analysis [AID452627, Type: Literature]
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6
[SID103176092]
Longevity-promoting activity in wild type Caenorhabditis elegans N2 assessed as decrease in DAF2 receptor mRNA expression at 50 ppm after 2 days by quantitative RT-PCR analysis [AID452628, Type: Literature]
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7
[SID103176092]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
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8
[SID103176092]
IC50 120Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production [AID454554, Type: Literature]Free fatty acid receptor 2 [gi:3122160]
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9
[SID103176092]
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production relative to acetate [AID454564, Type: Literature]Free fatty acid receptor 2 [gi:3122160]
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10
[SID103176092]
Toxicity in po dosed ICR mouse assessed as decreased in mobility after 3 hrs [AID498773, Type: Literature]
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11
[SID103176092]
Toxicity in po dosed mouse [AID498775, Type: Literature]
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12
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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13
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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14
[SID103176092]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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15
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia [AID625279, Type: Literature]
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16
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis [AID625280, Type: Literature]
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17
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis [AID625281, Type: Literature]
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18
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis [AID625282, Type: Literature]
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19
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests [AID625283, Type: Literature]
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20
[SID103176092]
Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure [AID625284, Type: Literature]
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