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Aminolevulinic Acid (CID 137) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(11)
 
 
Inactive(14)
 
 
Unspecified(85)
 
 
Top Targets:
Anthrax-tox M(3)
 
 
MFS(3)
 
 
Toxin trans(3)
 
 
Neur chan LBD(1)
 
 
PTR2(1)
 
 
BioAssay Types:
Literature(110)
 
 
 
 
BioActivity Types:
IC50(7)
 
 
 
Ki(3)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 110   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103182993]
IC50 12.9Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp method [AID406571, Type: Literature]Gamma-aminobutyric acid receptor subunit rho-1 [gi:223590210]
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2
[SID103182993]
Induction of apoptosis in human U251 cells assessed as increase in full length caspase 8 level after 24 hrs by Western blot [AID347584, Type: Literature]
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3
[SID103182993]
Increase in ROS production in human U251 cells at 100 uM after 4 hrs by FACS [AID347396, Type: Literature]
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4
[SID103182993]
Inhibition of 26S proteasome activity in human U251 cells at 1 mM after 48 hrs [AID347411, Type: Literature]
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5
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 0.1 mM followed by irradiation at 120 J.cm2 light [AID519379, Type: Literature]
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6
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 40 mM followed by irradiation at 120 J.cm2 light [AID519380, Type: Literature]
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7
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 exposed to irradiation at 120 J.cm2 light by HPLC [AID519381, Type: Literature]
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8
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 assessed as uroporphyrin level exposed to irradiation at 120 J.cm2 light by HPLC [AID519382, Type: Literature]
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9
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 assessed as protoporphyrin level exposed to irradiation at 120 J.cm2 light by HPLC [AID519383, Type: Literature]
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10
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 40 mM for 4 hrs under dark condition [AID519389, Type: Literature]
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11
[SID103182993]
Increase in heme level in human U251 cells assessed as porphobilinogen deaminase level at 100 uM after 2 hrs by Western blot in presence of cycloheximide [AID347405, Type: Literature]
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12
[SID103182993]
Ki 230TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells [AID681124, Type: Literature]Solute carrier family 15 member 2 [gi:2499990]
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13
[SID103182993]
Ki 790Inhibition constant (Ki) for human intestinal peptide carrier [AID92023, Type: Literature]
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14
[SID103182993]
IC50 1570Cytotoxicity against human HL60 cells after 72 hrs by MTT assay [AID347393, Type: Literature]
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15
[SID103182993]
IC50 1735Cytotoxicity against human MCF7 cells after 72 hrs by Hoechst test [AID347394, Type: Literature]
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16
[SID103182993]
Ki 2200TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells [AID681125, Type: Literature]Solute carrier family 15 member 1 [gi:1730492]
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17
[SID103182993]
IC50 2665Cytotoxicity against human U251 cells after 72 hrs by Hoechst test [AID347392, Type: Literature]
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18
[SID103182993]
IC50 2715Antiproliferative activity against human U251 cells assessed as PpIX release pretreated 72 hrs before 360-410 nm light photosensitization measured after 48 hrs by Hoechst test [AID347409, Type: Literature]
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19
[SID103182993]
IC50 2719Antiproliferative activity against human U251 cells assessed as PpIX release after 72 hrs by Hoechst test [AID347408, Type: Literature]
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20
[SID103182993]
IC50 3475Cytotoxicity against human MCF7/DX cells after 72 hrs by Hoechst test [AID347395, Type: Literature]
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