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Ibuprofen (CID 3672) - Compound BioActivity Data
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Filters: All Data » prostaglandin endoperoxide synthase      
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BioActivity Outcomes:
Active(55)
 
 
Inactive(2)
 
 
Unspecified(13)
 
 
Top Targets:
prostaglandin..(70)
 
 
 
 
BioAssay Types:
Literature(66)
 
 
 
 
BioActivity Types:
IC50(55)
 
 
 
Ki(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 68    Data Row: 70   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103174500]
IC50 0.212DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) [AID625243, Type: other]Prostaglandin G/H synthase 1 [gi:317373262]
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2
[SID103174500]
IC50 1.06Reverisible competitive inhibition of prostaglandin G/H synthase 1 [AID162150, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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3
[SID103174500]
IC50 1.1Inhibition of bovine COX2 by enzyme immunoassay [AID393820, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914301]
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4
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID288822, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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5
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID344874, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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6
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immunoassay [AID352496, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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7
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID368229, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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8
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID648862, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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9
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID724444, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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10
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID461113, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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11
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID622556, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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12
[SID103174500]
IC50 1.1In vitro inhibitory concentration against COX-2 enzyme [AID240796, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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13
[SID103174500]
IC50 1.1Inhibition of human recombinant COX-2 by enzyme immuno assay [AID443725, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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14
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID447529, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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15
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID457929, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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16
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immuno assay [AID474248, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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17
[SID103174500]
IC50 1.1Inhibition of human COX2 by enzyme immunoassay [AID494635, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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18
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immuno assay [AID603429, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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19
[SID103174500]
IC50 1.35Inhibition of human COX2 expressed in baculovirus system [AID664057, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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20
[SID103174500]
IC50 1.4Inhibition of human recombinant COX-2 [AID587449, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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21
[SID103174500]
IC50 2.9Inhibition of bovine COX1 by enzyme immunoassay [AID393818, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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22
[SID103174500]
IC50 2.9Inhibition of bovine COX-1 by enzyme immuno assay [AID443726, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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23
[SID103174500]
IC50 2.9Inhibition of ovine COX1 [AID724443, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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24
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID622474, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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25
[SID103174500]
IC50 2.9Inhibition of ovine COX1 [AID648861, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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26
[SID103174500]
IC50 2.9In vitro inhibitory concentration against COX-1 enzyme [AID240795, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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27
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID288821, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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28
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID344873, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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29
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID352495, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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30
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID368225, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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31
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID447528, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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32
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immunoassay [AID457928, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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33
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID461111, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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34
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID474247, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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35
[SID103174500]
IC50 2.9Inhibition of sheep COX1 by enzyme immunoassay [AID494634, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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36
[SID103174500]
IC50 2.9Inhibition of ovine COX1 by enzyme immuno assay [AID603428, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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37
[SID103174500]
IC50 3Inhibition of Prostaglandin G/H synthase 1 (COX-1). [AID161680, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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38
[SID103174500]
IC50 4Inhibition of ovine COX-1 [AID587448, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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39
[SID103174500]
IC50 5Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassay [AID701504, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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40
[SID103174500]
IC50 6.2Inhibition of COX2 in human whole blood after 15 mins [AID299910, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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41
[SID103174500]
IC50 6.9Inhibition of COX1 in human whole blood after 15 mins [AID299909, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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42
[SID103174500]
Ki 9Inhibition of sheep placental cotyledons COX1 [AID664053, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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43
[SID103174500]
IC50 12Inhibition of ovine COX-1 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid by HPLC analysis [AID614601, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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44
[SID103174500]
IC50 12Inhibition of ovine COX1 after 5 mins [AID492859, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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45
[SID103174500]
IC50 13Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production [AID399401, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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46
[SID103174500]
IC50 14.4Inhibitory concentration against Prostaglandin G/H synthase 1 of ram seminal vesicles at 100 uM [AID242201, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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47
[SID103174500]
IC50 18Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 mins [AID399404, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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48
[SID103174500]
IC50 25.53DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) [AID625244, Type: other]Prostaglandin G/H synthase 2 [gi:3915797]
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49
[SID103174500]
IC50 30Inhibition of Prostaglandin G/H synthase 2 (COX-2). [AID160237, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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50
[SID103174500]
IC50 36Inhibition of human COX2 pre-incubated for 10 mins before substrate addition by enzyme immunoassay [AID701505, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
View