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hydrazine (CID 9321) - Compound BioActivity Data
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Filters: All Data » p450      
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BioActivity Outcomes:
Unspecified(8)
 
 
Top Targets:
p450(8)
 
 
BioAssay Types:
Confirmatory(7)
 
 
BioActivity Types:
IC50(7)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123092331]
IC50 DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) [AID625229, Type: confirmatory]Thromboxane-A synthase [gi:254763392]
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2
[SID123092331]
IC50 DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625245, Type: confirmatory]Cytochrome P450 1A2 [gi:117144]
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3
[SID123092331]
DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625246, Type: other]Cytochrome P450 2A6 [gi:308153612]
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4
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: confirmatory]Cytochrome P450 2C19 [gi:60416369]
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5
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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6
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625249, Type: confirmatory]Cytochrome P450 2D6 [gi:84028191]
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7
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625250, Type: confirmatory]Cytochrome P450 2E1 [gi:117250]
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8
[SID123092331]
IC50 DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) [AID625251, Type: confirmatory]Cytochrome P450 3A4 [gi:116241312]
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