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axitinib (CID 6450551) - Compound BioActivity Data
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Filters: All Data » STKc AGC      
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BioActivity Outcomes:
Active(8)
 
 
Unspecified(11)
 
 
Top Targets:
STKc AGC(19)
 
 
 
BioAssay Types:
Literature(19)
 
 
 
BioActivity Types:
Kd(17)
 
 
 
IC50(1)
 
 
Ki(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 19    Data Row: 19   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123098392]
Kd 0.0013Binding constant for AURKC kinase domain [AID624769, Type: Literature]Aurora kinase C [gi:27805738]
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2
[SID123098392]
Ki 0.0042Inhibition of human PLK4 [AID762206, Type: Literature]Serine/threonine-protein kinase PLK4 [gi:160113150]
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3
[SID123098392]
Kd 0.011Binding constant for AURKB kinase domain [AID624772, Type: Literature]Aurora kinase B [gi:317373473]
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4
[SID123098392]
Kd 0.016Binding constant for PLK4 kinase domain [AID625076, Type: Literature]Serine/threonine-protein kinase PLK4 [gi:160113150]
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5
[SID123098392]
IC50 0.046Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ELISA assay [AID762246, Type: Literature]Serine/threonine-protein kinase PLK4 [gi:160113150]
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6
[SID123098392]
Kd 0.072Binding constant for AURKA kinase domain [AID624919, Type: Literature]Aurora kinase A [gi:27923855]
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7
[SID123098392]
Kd 0.67Binding constant for ULK3 kinase domain [AID624818, Type: Literature]Serine/threonine-protein kinase ULK3 [gi:259016166]
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8
[SID123098392]
Kd 1.5Binding constant for CAMKK2 kinase domain [AID625060, Type: Literature]Calcium/calmodulin-dependent protein kinase kinase 2 [gi:317373374]
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9
[SID123098392]
Kd 10Binding constant for CAMK4 kinase domain [AID624843, Type: Literature]Calcium/calmodulin-dependent protein kinase type IV [gi:2499586]
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10
[SID123098392]
Kd 10Binding constant for DCAMKL3 kinase domain [AID624707, Type: Literature]Serine/threonine-protein kinase DCLK3 [gi:115502142]
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11
[SID123098392]
Kd 10Binding constant for CAMK2G kinase domain [AID624731, Type: Literature]Calcium/calmodulin-dependent protein kinase type II subunit gamma [gi:62512173]
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12
[SID123098392]
Kd 10Binding constant for SNRK kinase domain [AID624752, Type: Literature]SNF-related serine/threonine-protein kinase [gi:90185235]
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13
[SID123098392]
Kd 10Binding constant for AMPK-alpha1 kinase domain [AID624773, Type: Literature]5'-AMP-activated protein kinase catalytic subunit alpha-1 [gi:254763436]
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14
[SID123098392]
Kd 10Binding constant for PHKG2 kinase domain [AID624797, Type: Literature]Phosphorylase b kinase gamma catalytic chain, liver/testis isoform [gi:125536]
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15
[SID123098392]
Kd 10Binding constant for CAMK1 kinase domain [AID624922, Type: Literature]Calcium/calmodulin-dependent protein kinase type 1 [gi:3122301]
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16
[SID123098392]
Kd 10Binding constant for AMPK-alpha2 kinase domain [AID625047, Type: Literature]5'-AMP-activated protein kinase catalytic subunit alpha-2 [gi:20178276]
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17
[SID123098392]
Kd 10Binding constant for CAMK1D kinase domain [AID625118, Type: Literature]Calcium/calmodulin-dependent protein kinase type 1D [gi:56404610]
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18
[SID123098392]
Kd 10Binding constant for CAMK1G kinase domain [AID625119, Type: Literature]Calcium/calmodulin-dependent protein kinase type 1G [gi:73620970]
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19
[SID123098392]
Kd 10Binding constant for STK33 kinase domain [AID625138, Type: Literature]Serine/threonine-protein kinase 33 [gi:74761329]
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