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BioActivity Data for Compound (2R,3R)-2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(4-fluoro-2-methyl-phenyl)-6-(3-hydroxy-2-hydroxymethyl-pyrrolidin-1-yl)-pyridin-3-yl]-N-methyl-isobutyramide (CID 60196441)

Filters: All Data » NR LBD Fxr      
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BioActivity Outcomes:
Inconclusive(4)
 
 
Top Targets:
NR LBD Fxr(4)
 
 
BioAssay Types:
Confirmatory(2)
 
 
Summary(2)
 
 
BioActivity Types:
Potency(3)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213906]
Potency-Replicate_1 10.7973qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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2
[SID144213906]
Potency-Replicate_1 30.4311qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743220, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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3
[SID144213906]
Ratio Potency (uM) 35.48qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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4
[SID144213906]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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