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Ibuprofen (CID 3672) - Compound BioActivity Data
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Filters: All Data » MFS      
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(14)
 
 
Top Targets:
MFS(16)
 
 
 
BioAssay Types:
Literature(16)
 
 
 
BioActivity Types:
Ki(4)
 
 
 
IC50(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 16    Data Row: 16   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103174500]
Ki 1.12202Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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2
[SID103174500]
Ki 4.67735Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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3
[SID103174500]
Ki 3.5TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes [AID681340, Type: Literature]Solute carrier family 22 member 6 [gi:81886651]
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4
[SID103174500]
IC50 8TP_TRANSPORTER: inhibition of Adefovir uptake in OAT1-expressing CHO cells [AID681160, Type: Literature]Solute carrier family 22 member 6 [gi:74762955]
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5
[SID103174500]
Ki 1170TP_TRANSPORTER: inhibition of MTX uptake in OAT3-expressing S2 cells [AID681372, Type: Literature]Solute carrier family 22 member 8 [gi:74730587]
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6
[SID103174500]
TP_TRANSPORTER: inhibition of E1S uptake (E1S: 0.05 uM, Ibuprofen: 5 uM) in Xenopus laevis oocytes [AID682131, Type: Literature]Solute carrier family 22 member 8 [gi:74730587]
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7
[SID103174500]
Activity of mouse Oat6 expressed in Xenopus oocytes assessed as drug uptake [AID360152, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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8
[SID103174500]
Activity of mouse Oat1 expressed in Xenopus oocytes assessed as drug uptake [AID360153, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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9
[SID103174500]
Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells at 100 uM by confocal microscopy [AID386623, Type: Literature]Solute carrier family 22 member 1 [gi:313104181]
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10
[SID103174500]
IC50 TP_TRANSPORTER: inhibition of MTX uptake in Xenopus laevis oocytes [AID678787, Type: Literature]Solute carrier family 22 member 6 [gi:81886651]
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11
[SID103174500]
TP_TRANSPORTER: inhibition of PHA uptake (PHA: 1000uM) in mOat3-expressing oocytes [AID678841, Type: Literature]Solute carrier family 22 member 8 [gi:124015184]
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12
[SID103174500]
TP_TRANSPORTER: inhibition of MTX uptake (MTX: 1 uM, Ibuprofen: 1000 uM) in OAT1-expressing S2 cells [AID679546, Type: Literature]Solute carrier family 22 member 6 [gi:74762955]
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13
[SID103174500]
TP_TRANSPORTER: uptake in OAT1-expressing CHO cells [AID679830, Type: Literature]Solute carrier family 22 member 6 [gi:74762955]
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14
[SID103174500]
TP_TRANSPORTER: inhibition of MTX uptake (MTX: 1 uM, Ibuprofen: 1000 uM) in OAT4-expressing S2 cells [AID680177, Type: Literature]Solute carrier family 22 member 11 [gi:74734337]
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15
[SID103174500]
TP_TRANSPORTER: inhibition of E1S uptake (E1S: 0.05 uM, Ibuprofen: 500 uM) in Xenopus laevis oocytes [AID680191, Type: Literature]Solute carrier family 22 member 11 [gi:74734337]
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16
[SID103174500]
Km TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID681141, Type: Literature]Solute carrier family 22 member 8 [gi:74730587]
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