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Cyclic AMP (CID 6076) - Compound BioActivity Data
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Filters: All Data » ABCC MRP domain2      
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BioActivity Outcomes:
Unspecified(10)
 
 
Top Targets:
ABCC MRP doma..(10)
 
 
BioAssay Types:
Literature(10)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103317043]
Km 44.5TP_TRANSPORTER: uptake in membrane vesicles from MRP4-expressing Sf9 cells [AID679496, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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2
[SID103317043]
Km 379TP_TRANSPORTER: uptake in membrane vesicles from MRP5-expressing V79 cells [AID680352, Type: Literature]Multidrug resistance-associated protein 5 [gi:8928547]
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3
[SID103317043]
TP_TRANSPORTER: inhibition of cGMP uptake (cGMP: 5 uM, cAMP: 500 uM) in membrane vesicles from MRP5-expressing V79 cells [AID681864, Type: Literature]Multidrug resistance-associated protein 5 [gi:8928547]
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4
[SID103317043]
TP_TRANSPORTER: inhibition of cGMP uptake (cGAMP: 1 uM, cAMP: 250 uM) in membrane vesicles from MRP4-expressing Sf9 cells [AID681878, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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5
[SID103317043]
TP_TRANSPORTER: inhibition of MTX uptake (MTX: 20 uM, cAMP: 300 uM) in membrane vesicles from MRP4-expressing Sf9 cells [AID681905, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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6
[SID103317043]
TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 1 uM, cAMP: 300 uM) in membrane vesicles from MRP4-expressing Sf9 cells [AID681923, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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7
[SID103317043]
TP_TRANSPORTER: efflux in MRP4-expressing HepG2 cells [AID682097, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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8
[SID103317043]
TP_TRANSPORTER: ATP-dependent uptake of cAMP at a concentration of 10 uM in membrane vesicle from MRP8-expressing LLC-PK1 cells [AID682111, Type: Literature]ATP-binding cassette sub-family C member 11 [gi:74762666]
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9
[SID103317043]
TP_TRANSPORTER: efflux in MRP8-1-expressing LLC-PK1 cells [AID679657, Type: Literature]ATP-binding cassette sub-family C member 11 [gi:74762666]
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10
[SID103317043]
Substrates of transporters of clinical importance in the absorption and disposition of drugs, MRP4 [AID588979, Type: Literature]Multidrug resistance-associated protein 4 [gi:206729914]
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