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Acetylcholine (CID 187) - Compound BioActivity Data
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Filters: All Data » 7TM GPCR Srx      
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BioActivity Outcomes:
Active(6)
 
 
Unspecified(7)
 
 
Top Targets:
7TM GPCR Srx(13)
 
 
 
BioAssay Types:
Literature(13)
 
 
 
BioActivity Types:
EC50(6)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 13    Data Row: 13   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104234160]
EC50 0.0011Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay [AID511592, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113118]
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2
[SID104234160]
EC50 0.0011Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based staining [AID672151, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113118]
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3
[SID104234160]
EC50 0.0012Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay [AID511603, Type: Literature]Muscarinic acetylcholine receptor M5 [gi:543761]
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4
[SID104234160]
EC50 0.0012Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as calcium mobilization for 6 mins by Calcium4-based staining [AID672153, Type: Literature]Muscarinic acetylcholine receptor M5 [gi:543761]
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5
[SID104234160]
EC50 0.0032Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay [AID511597, Type: Literature]Muscarinic acetylcholine receptor M3 [gi:113125]
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6
[SID104234160]
EC50 0.0032Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as calcium mobilization for 6 mins by Calcium4-based staining [AID672157, Type: Literature]Muscarinic acetylcholine receptor M3 [gi:113125]
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7
[SID104234160]
Displacement of [3H]NMS from human cloned muscarinic M5 receptor expressed in CHO cells [AID313858, Type: Literature]Muscarinic acetylcholine receptor M5 [gi:543761]
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8
[SID104234160]
Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as calcium mobilization atb 10 uM for 6 mins by Calcium4-based staining relative to acetylcholine [AID672156, Type: Literature]Muscarinic acetylcholine receptor M3 [gi:113125]
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9
[SID104234160]
Agonist activity at muscarinic M1 receptor in Wistar rat cerebral cortex assessed as [3H]myoinositol (1,4,5)-triphosphate level per gram of protein at 20 uM after 1 hr by liquid scintillation counting (RVb = 0.64 +/- 0.12 pmol) [AID477467, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113121]
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10
[SID104234160]
Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cells [AID313856, Type: Literature]Muscarinic acetylcholine receptor M3 [gi:113125]
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11
[SID104234160]
Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based staining relative to acetylcholine [AID672150, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113118]
View
12
[SID104234160]
Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cells [AID313854, Type: Literature]Muscarinic acetylcholine receptor M1 [gi:113118]
View
13
[SID104234160]
Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as calcium mobilization at 10 uM for 6 mins by Calcium4-based staining relative to acetylcholine [AID672152, Type: Literature]Muscarinic acetylcholine receptor M5 [gi:543761]
View