Bookmark and Share
Dopamine (CID 681) - Compound BioActivity Data
.
Filters: All Data » 7TM GPCR Srsx      
Filter selected
BioActivity Outcomes:
Active(63)
 
 
Inactive(4)
 
 
Unspecified(19)
 
 
Top Targets:
7TM GPCR Srsx(86)
 
 
 
 
BioAssay Types:
Literature(82)
 
 
 
 
Screening(2)
 
 
Confirmatory(1)
 
 
BioActivity Types:
Ki(29)
 
 
EC50(26)
 
 
IC50(6)
 
 
Kd(1)
 
 
Potency(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 84    Data Row: 86   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167911]
EC50 0.0011Agonist activity at rat D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274445, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
2
[SID103167911]
EC50 0.0018Agonist activity at dopamine D3 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay [AID750640, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
3
[SID103167911]
Ki 0.00189Displacement of [3H]quinpirole from human dopamine D2A receptors expressed in LtK cells [AID61612, Type: Literature]D(2) dopamine receptor [gi:118206]
View
4
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
5
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(3) dopamine receptor [gi:118211]
View
6
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
7
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(3) dopamine receptor [gi:118211]
View
8
[SID103167911]
Ki 0.0029Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells [AID458633, Type: Literature]D(2) dopamine receptor [gi:118206]
View
9
[SID103167911]
EC50 0.00476Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay [AID461563, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
10
[SID103167911]
EC50 0.00476Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID513742, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
11
[SID103167911]
EC50 0.005Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production [AID272396, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
12
[SID103167911]
EC50 0.0058Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assay [AID712282, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
13
[SID103167911]
EC50 0.0061Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine incorporation assay [AID709655, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
14
[SID103167911]
EC50 0.0067Agonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay [AID750644, Type: Literature]D(2) dopamine receptor [gi:118206]
View
15
[SID103167911]
EC50 0.00764Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counting analysis [AID750042, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
16
[SID103167911]
EC50 0.00853Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding [AID446402, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
17
[SID103167911]
EC50 0.00853Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS binding [AID425420, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
18
[SID103167911]
EC50 0.00853Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S binding [AID312287, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
19
[SID103167911]
EC50 0.00853Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS binding [AID384700, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
20
[SID103167911]
EC50 0.00857Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay [AID690847, Type: Literature]D(3) dopamine receptor [gi:1169206]
View