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Morphine (CID 5288826) - Compound BioActivity Data
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Filters: All Data » 7TM GPCR Srsx      
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BioActivity Outcomes:
Active(39)
 
 
Inconclusive(1)
 
 
Unspecified(7)
 
 
Top Targets:
7TM GPCR Srsx(47)
 
 
 
 
BioAssay Types:
Literature(45)
 
 
 
 
Confirmatory(2)
 
 
BioActivity Types:
Ki(24)
 
 
 
 
IC50(13)
 
 
EC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 47    Data Row: 47   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103169185]
IC50 0.00182Inhibition of [3H]U-69593 radioligand binding to Guinea pig opioid receptor kappa 1. [AID148680, Type: Literature]Kappa-type opioid receptor [gi:730228]
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2
[SID103169185]
IC50 0.0042Displacement [3H]naloxone from rat-brain Opioid receptors [AID150397, Type: Literature]Kappa-type opioid receptor [gi:464313]
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3
[SID103169185]
IC50 0.022Displacement of [3H]naloxone from rat brain Opioid receptors [AID150260, Type: Literature]Kappa-type opioid receptor [gi:464313]
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4
[SID103169185]
Ki 0.024Binding affinity to displace radioligand [3H]U-69593 on Opioid receptor kappa 1 in guinea pig membranes. [AID149256, Type: Literature]Kappa-type opioid receptor [gi:730228]
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5
[SID103169185]
Ki 0.024Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593 [AID149262, Type: Literature]Kappa-type opioid receptor [gi:730228]
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6
[SID103169185]
Ki 0.024Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brain [AID410725, Type: Literature]Kappa-type opioid receptor [gi:730228]
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7
[SID103169185]
IC50 0.027Displacement of [3H]nalotrexone from rat-brain Opioid receptors [AID150396, Type: Literature]Kappa-type opioid receptor [gi:464313]
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8
[SID103169185]
Ki 0.027Inhibition of 9 (2 nM) binding to Opioid receptor kappa 1 of rat brain homogenate [AID148595, Type: confirmatory]Kappa-type opioid receptor [gi:464313]
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9
[SID103169185]
Ki 0.0339Displacement of radiolabeled U69593 from kappa1 opioid receptor in Hartley guinea pig brain [AID268679, Type: Literature]Kappa-type opioid receptor [gi:730228]
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10
[SID103169185]
Ki 0.0469Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum homogenate by scintillation counting [AID603728, Type: Literature]Kappa-type opioid receptor [gi:730228]
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11
[SID103169185]
Ki 0.049Binding affinity towards opioid receptor kappa 1 [AID149264, Type: Literature]Kappa-type opioid receptor [gi:730228]
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12
[SID103169185]
Ki 0.0543Displacement of [3H]-U69593 from kappa opioid receptor in guinea pig cerebellum homogenates [AID603513, Type: Literature]Kappa-type opioid receptor [gi:730228]
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13
[SID103169185]
Ki 0.0691Binding affinity towards Opioid receptor kappa 1 using [3H]U-69593 as radioligand. [AID149261, Type: Literature]Kappa-type opioid receptor [gi:730228]
View
14
[SID103169185]
Ki 0.086Binding affinity for the Opioid receptor kappa 1 [AID149131, Type: Literature]Kappa-type opioid receptor [gi:730228]
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15
[SID103169185]
Ki 0.11Binding affinity against Opioid receptor kappa 1 in guinea pig brain membranes [AID149117, Type: Literature]Kappa-type opioid receptor [gi:730228]
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16
[SID103169185]
IC50 0.13Binding to kappa opioid receptor by using [3H]U-69593 as radioligand in guinea pig cerebellum [AID95208, Type: confirmatory]Kappa-type opioid receptor [gi:730228]
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17
[SID103169185]
IC50 0.1451Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contraction [AID389657, Type: Literature]Kappa-type opioid receptor [gi:464312]
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18
[SID103169185]
Ki 0.151Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pig [AID149135, Type: Literature]Kappa-type opioid receptor [gi:730228]
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19
[SID103169185]
Ki 0.151Displacement of [3H]U-69593 from kappa opioid receptors in guine pig brain (minus cerebellum). [AID147979, Type: Literature]Kappa-type opioid receptor [gi:730228]
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20
[SID103169185]
Ki 0.167Binding affinity to Opioid receptor kappa 1 in guinea pig cortex using [3H]EKC as radioligand [AID149268, Type: Literature]Kappa-type opioid receptor [gi:730228]
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