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BioActivity Data for Compound axitinib (CID 6450551)

Filters: All Data » Inactive      
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BioActivity Outcomes:
Inactive(71)
 
 
Top Targets:
NR LBD AR(4)
 
 
7tm 4(2)
 
 
ACD HspB1 lik..(2)
 
 
NR LBD GR(2)
 
 
Glutaminase(1)
 
 
BioAssay Types:
Confirmatory(56)
 
 
Screening(9)
 
 
Summary(5)
 
 
BioAssay Categories:
Toxicity(1)
 
 
Cell-based(12)
 
 
BioActivity Types:
Potency(51)
 
 
AC50(5)
 
 
IC50(5)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 71    Data Row: 71   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207146]
Potency-Replicate_1 0.5956qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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2
[SID144207146]
Potency 1.4818Cell Proliferation Assay against the TMD8 Cell Line (Caspase readout at 8 hrs) [AID651713, Type: confirmatory]
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3
[SID144207146]
Potency 1.8655Cell Proliferation Assay against a hMSC Cell Line [AID651696, Type: confirmatory]
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4
[SID144207146]
Potency-Replicate_1 3.3491qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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5
[SID170466656]
Ac50 3.98107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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6
[SID170466656]
Ac50 6.10778qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 4, green channel [AID1117316, Type: confirmatory]
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7
[SID170466656]
Ac50 8.91251qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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8
[SID170466656]
IC50 10Decreased HeLa cell count-IC50 [AID1117347, Type: confirmatory]
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9
[SID170466656]
IC50 10Increased HeLa cells with 2N DNA content-IC50 [AID1117349, Type: confirmatory]
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10
[SID170466656]
IC50 10Increased chromatin condensation in HeLa cells-IC50 [AID1117350, Type: confirmatory]
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11
[SID170466656]
IC50 10Increased HeLa cells with 4N DNA content-IC50 [AID1117351, Type: confirmatory]
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12
[SID170466656]
IC50 10VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (viability)-IC50 [AID1117324, Type: confirmatory]
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13
[SID144207146]
Potency 16.7744qHTS profiling for inhibitors of Plasmodium falciparum (DD2) proliferation [AID743323, Type: confirmatory]
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14
[SID144207146]
Potency 18.8212qHTS profiling for inhibitors of Plasmodium falciparum (3D7) proliferation [AID743322, Type: confirmatory]
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15
[SID144207146]
Potency 20.931qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
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16
[SID144207146]
Potency 20.931Cell Proliferation Assay against the HBL1 Cell Line [AID651646, Type: confirmatory]
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17
[SID170466656]
Ac50 27.2824qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 4, ratio channel [AID1117308, Type: confirmatory]
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18
[SID170466656]
Ac50 27.2824qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 4, blue channel [AID1117309, Type: confirmatory]
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19
[SID144207146]
Potency qHTS profiling for inhibitors of Plasmodium falciparum (HB3) proliferation [AID743324, Type: confirmatory]
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20
[SID144207146]
Potency Cell Proliferation Assay Versus the ED40515 IL2 Dependent ATL cell lines [AID1053195, Type: confirmatory]
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