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Aspirin (CID 2244) - Compound BioActivity Data
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Filters: All Data » Inactive      
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BioActivity Outcomes:
Inactive(1513)
 
 
Top Targets:
NR LBD PPAR(38)
 
 
NR LBD ER(28)
 
 
NR LBD AR(26)
 
 
NR LBD TR(25)
 
 
NR LBD VDR(21)
 
 
BioAssay Types:
Confirmatory(898)
 
 
Screening(361)
 
 
Literature(117)
 
 
Summary(72)
 
 
BioActivity Types:
Potency(776)
 
 
IC50(15)
 
 
EC50(9)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 920    Data Row: 1513   Total Pages: 76   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID174007205]
Potency 0.0012qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation [AID743347, Type: confirmatory]
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2
[SID174007205]
Potency 0.0013qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
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3
[SID174007205]
Potency 0.0033qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation [AID743345, Type: confirmatory]
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4
[SID50105490]
Potency 0.0224qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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5
[SID144209315]
Potency-Replicate_1 0.1727qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID90340586]
Potency 0.8913qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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7
[SID17389202]
Potency 1.9953qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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8
[SID17389202]
Potency 8.4127qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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9
[SID90340586]
Potency 11.2202qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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10
[SID17390036]
Potency 12.5893qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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11
[SID174007205]
Potency 23.6945qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
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12
[SID144203627]
Potency-Replicate_1 23.7101qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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13
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID2021, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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14
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID2022, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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15
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID2038, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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16
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant [AID2043, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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17
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID2036, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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18
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant [AID2039, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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19
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype [AID2040, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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20
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID2046, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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