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Acetic Acid (CID 176) - Compound BioActivity Data
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Filters: All Data » Inactive      
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BioActivity Outcomes:
Inactive(97)
 
 
Top Targets:
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD PPAR(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Confirmatory(60)
 
 
Summary(24)
 
 
Literature(11)
 
 
BioActivity Types:
Potency(78)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 96    Data Row: 97   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211770]
Potency-Replicate_1 0.0195qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144211770]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID144211770]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID144211770]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID144211770]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID144211770]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID144211770]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144211770]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144211770]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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10
[SID422198]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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11
[SID476220]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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12
[SID103176092]
Inhibition of calf DNA polymerase alpha using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins [AID627874, Type: Literature]
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13
[SID103176092]
Inhibition of histidine-tagged human DNA polymerase gamma using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins [AID627875, Type: Literature]
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14
[SID103176092]
Inhibition of calf DNA polymerase alpha using bovine deoxyribonuclease 1-treated DNA and dNTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins [AID627877, Type: Literature]
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15
[SID103176092]
Inhibition of histidine-tagged human DNA polymerase gamma using bovine deoxyribonuclease 1-treated DNA and dNTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins [AID627878, Type: Literature]
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16
[SID103176092]
LD50 Cytotoxicity against human HCT116 cells by WST-1 assay [AID627976, Type: Literature]
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17
[SID103176092]
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha secretion at 5 uM treated 30 mins before LPS challenge measured after 24 hrs by ELISA [AID627979, Type: Literature]
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18
[SID103176092]
Antiinflammatory activity in mouse assessed as inhibition of TPA-induced mouse ear edema at 500 ug/ear administered 30 mins before TPA challenge measured after 7 hrs relative to untreated control [AID627982, Type: Literature]
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19
[SID144211770]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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20
[SID144211770]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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