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Catechin (CID 9064) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(35)
 
 
Top Targets:
prostaglandin..(3)
 
 
7TM GPCR Srx(2)
 
 
JmjC(2)
 
 
PIN FEN1(2)
 
 
Ape1-like AP-..(1)
 
 
BioAssay Types:
Literature(24)
 
 
Confirmatory(8)
 
 
Screening(2)
 
 
BioActivity Types:
IC50(12)
 
 
Potency(8)
 
 
Kd(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 33    Data Row: 35   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123094711]
IC50 1.61Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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2
[SID123094711]
IC50 2.31Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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3
[SID123094711]
ID50 2.75Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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4
[SID123094711]
ID50 2.86Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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5
[SID123094711]
IC50 2.9Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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6
[SID123094711]
IC50 4.1Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay [AID333439, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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7
[SID123094711]
IC50 4.3Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry [AID650645, Type: Literature]
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8
[SID90341637]
Potency 4.7444qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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9
[SID90341637]
Potency 4.7444qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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10
[SID123094711]
IC50 5.3Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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11
[SID50105958]
Potency 11.2202qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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12
[SID50105958]
Potency 12.5893qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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13
[SID123094711]
IC50 13.1Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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14
[SID26753531]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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15
[SID123094711]
IC50 20.2Free radical scavenging activity of DPPH was determined; value taken from reference 11 [AID226690, Type: Literature]
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16
[SID123094711]
IC50 20.2Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay [AID333440, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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17
[SID123094711]
IC50 21.1Inhibition of Saccharomyces cerevisiae alcohol dehydrogenase measured every 5 mins for 2 hrs by spectrophotometry [AID650644, Type: Literature]
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18
[SID50105958]
Potency 25.1189qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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19
[SID50105958]
Potency 28.1838qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
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20
[SID50105958]
Potency 28.1838qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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21
[SID123094711]
IC50 36.7Inhibition of COX1 [AID332217, Type: Literature]
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22
[SID123094711]
Kd 40.7Binding affinity to COX1 in sheep seminal vesicle [AID333444, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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23
[SID123094711]
IC50 49Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356646, Type: Literature]
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24
[SID123094711]
Antioxidant activity assessed as DPPH radical scavenging activity [AID311580, Type: Literature]
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25
[SID123094711]
Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS assay [AID311282, Type: Literature]Delta-type opioid receptor [gi:311033488]
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26
[SID123094711]
Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S assay [AID311280, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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27
[SID48415778]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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28
[SID17404782]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]90-kda heat shock protein beta HSP90 beta [Homo sapiens] [gi:4261762]
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29
[SID17404782]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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30
[SID123094711]
Antioxidant activity assessed as peroxyl radical scavenging activity at 1 to 2 uM by ORAC assay [AID551461, Type: Literature]
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31
[SID123094711]
Induction of supercoiled pSP64 plasmid DNA cleavage assessed as increase in linear duplex form 3 at 10 uM by agarose gel electrophoresis [AID377528, Type: Literature]
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32
[SID123094711]
Antioxidant activity assessed as copper ion radical scavenging activity at 2 uM [AID551462, Type: Literature]
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33
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 1 mg/ml after 18 hrs using crystal violet staining [AID626983, Type: Literature]
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34
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 2 mg/ml after 18 hrs using crystal violet staining [AID626984, Type: Literature]
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35
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 3 mg/ml after 18 hrs using crystal violet staining [AID626985, Type: Literature]
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