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2-Anilino-1,4-naphthoquinone (CID 81124) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(85)
 
 
Top Targets:
DUF3371(5)
 
 
Peptidase C48(3)
 
 
SLT beta(2)
 
 
RIP(2)
 
 
RHD-n RelA(2)
 
 
BioAssay Types:
Confirmatory(60)
 
 
Screening(20)
 
 
Literature(5)
 
 
BioActivity Types:
AC50(27)
 
 
Potency(17)
 
 
IC50(5)
 
 
EC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 68    Data Row: 85   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103284973]
PD50 0.064Neuroprotective activity in mouse HT22 cells assessed as prevention from glutamate-induced oxidative cell death by MTS assay [AID736844, Type: Literature]
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2
[SID135659550]
AbsAC40_uM 0.175qPCR Assay for MITF Expression Measured in Cell-Based System Using RT-PCR - 2084-05_Inhibitor_Dose_DryPowder_Activity [AID651773, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
3
[SID135724474]
AbsAC40_uM 0.189qPCR Assay for MITF Expression Measured in Cell-Based System Using RT-PCR - 2084-05_Inhibitor_Dose_DryPowder_Activity [AID651773, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
4
[SID103284973]
EC50 0.239Inhibitory activity on acetylcholine-induced vasorelaxation of phenylephrine-precontracted rat aorta with intact endothelium [AID175494, Type: Literature]
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5
[SID135659550]
AbsAC40_uM 0.302qPCR Assay for DCT Expression Measured in Cell-Based System Using RT-PCR - 2084-12_Inhibitor_Dose_DryPowder_Activity [AID651771, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
6
[SID135724474]
AbsAC40_uM 0.323qPCR Assay for TRPM1 Expression Measured in Cell-Based System Using RT-PCR - 2084-09_Inhibitor_Dose_DryPowder_Activity [AID651770, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
7
[SID135724474]
AbsAC40_uM 0.325qPCR Assay for DCT Expression Measured in Cell-Based System Using RT-PCR - 2084-12_Inhibitor_Dose_DryPowder_Activity [AID651771, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
8
[SID135659550]
AbsAC40_uM 0.337qPCR Assay for MLANA Expression Measured in Cell-Based System Using RT-PCR - 2084-13_Inhibitor_Dose_DryPowder_Activity [AID651795, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
9
[SID135724474]
AbsAC40_uM 0.389qPCR Assay for MLANA Expression Measured in Cell-Based System Using RT-PCR - 2084-13_Inhibitor_Dose_DryPowder_Activity [AID651795, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
10
[SID135724474]
AbsAC40_uM 0.394qPCR Assay for CDK2 Expression Measured in Cell-Based System Using RT-PCR - 2084-11_Inhibitor_Dose_DryPowder_Activity [AID651772, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
11
[SID135659550]
AbsAC40_uM 0.571qPCR Assay for CDK2 Expression Measured in Cell-Based System Using RT-PCR - 2084-11_Inhibitor_Dose_DryPowder_Activity [AID651772, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
12
[SID135659550]
AbsAC40_uM 0.74qPCR Assay for TRPM1 Expression Measured in Cell-Based System Using RT-PCR - 2084-09_Inhibitor_Dose_DryPowder_Activity [AID651770, Type: confirmatory]microphthalmia-associated transcription factor, partial [Homo sapiens] [gi:7684294]
View
13
[SID24824101]
Potency 1qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
View
14
[SID135724474]
AC50_uM 1.18MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624427, Type: confirmatory]
View
15
[SID24824101]
EC50_uM 1.26Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) [AID435004, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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16
[SID24824101]
EC50 1.348Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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17
[SID24824101]
EC50 1.348Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]transcription factor p65 isoform 1 [Homo sapiens] [gi:223468676]
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18
[SID135659550]
AC50_uM 1.46MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID624289, Type: confirmatory]Microphthalmia-associated transcription factor [Homo sapiens] [gi:40807040]
View
19
[SID135659550]
AC50_uM 1.53MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624427, Type: confirmatory]
View
20
[SID24824101]
Potency 1.7783qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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