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Dopamine (CID 681) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(295)
 
 
Top Targets:
7tm 4(99)
 
 
alpha CA I II..(14)
 
 
alpha CA(10)
 
 
FAM101(5)
 
 
HSD10-like SD..(4)
 
 
BioAssay Types:
Literature(255)
 
 
Confirmatory(38)
 
 
Summary(1)
 
 
BioActivity Types:
Ki(88)
 
 
EC50(59)
 
 
IC50(48)
 
 
Potency(27)
 
 
Kd(6)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 280    Data Row: 295   Total Pages: 15   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167911]
IC50 8e-09Agonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]-Spiperone [AID62635, Type: Literature]
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2
[SID103167911]
EC50 0.0011Agonist activity at rat D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274445, Type: Literature]D(2) dopamine receptor [gi:47117674]
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3
[SID103167911]
EC50 0.0011In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay [AID61225, Type: Literature]
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4
[SID103167911]
Ki 0.0012Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4 [AID64028, Type: Literature]D(4) dopamine receptor [gi:1345939]
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5
[SID103167911]
Kd 0.00133Displacement of [3H]SCH23390 from dopamine D1-like receptor pig striatal membrane [AID515612, Type: Literature]
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6
[SID103167911]
EC50 0.0018Agonist activity at dopamine D3 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay [AID750640, Type: Literature]D(3) dopamine receptor [gi:1169206]
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7
[SID103167911]
Ki 0.0018Binding Affinity on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole was tested [AID62319, Type: Literature]
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8
[SID103167911]
Ki 0.00189Displacement of [3H]quinpirole from Dopamine receptor D2 [AID63075, Type: Literature]
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9
[SID103167911]
Ki 0.00189Displacement of [3H]quinpirole from human dopamine D2A receptors expressed in LtK cells [AID61612, Type: Literature]D(2) dopamine receptor [gi:118206]
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10
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(3) dopamine receptor [gi:118211]
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11
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(1A) dopamine receptor [gi:118229]
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12
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(1B) dopamine receptor [gi:118251]
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13
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(2) dopamine receptor [gi:47117674]
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14
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(4) dopamine receptor [gi:6226851]
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15
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(2) dopamine receptor [gi:47117674]
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16
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(4) dopamine receptor [gi:6226851]
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17
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(1A) dopamine receptor [gi:118229]
View
18
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(1B) dopamine receptor [gi:118251]
View
19
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(3) dopamine receptor [gi:118211]
View
20
[SID103167911]
EC50 0.0022Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274437, Type: Literature]D(4) dopamine receptor [gi:1345939]
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