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Cyclic AMP (CID 6076) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(14)
 
 
Top Targets:
7tm 4(1)
 
 
RasGEF(1)
 
 
BioAssay Types:
Literature(11)
 
 
Confirmatory(2)
 
 
Screening(1)
 
 
BioActivity Types:
IC50(2)
 
 
Potency(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103317043]
Km 0.05Inhibition of Phosphodiesterase 8 [AID158285, Type: Literature]CAMP-specific cyclic nucleotide phosphodiesterase PDE8 [gi:81864950]
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2
[SID103317043]
Km 0.2Inhibition of Phosphodiesterase 7 [AID158280, Type: Literature]
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3
[SID90340992]
Potency 0.3663HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Hit Validation in HTRF [AID624455, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
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4
[SID103317043]
Km 0.53Affinity for bovine heart phosphodiesterase [AID158420, Type: Literature]
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5
[SID103317043]
Km 0.56Affinity for rabbit lung phosphodiesterase [AID158735, Type: Literature]
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6
[SID103317043]
Km 0.56Inhibition of rabbit lung cAMP Phosphodiesterase [AID219819, Type: Literature]
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7
[SID103317043]
Km 0.71Activity of bovine aortic PDE4 [AID628762, Type: Literature]
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8
[SID103317043]
Km 0.79Affinity for rabbit kidney phosphodiesterase [AID158734, Type: Literature]
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9
[SID103317043]
Km 1.3Inhibition of bovine brain cAMP Phosphodiesterase [AID219691, Type: Literature]
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10
[SID50105813]
Potency 2.8184qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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11
[SID103317043]
IC50 40Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay [AID723507, Type: Literature]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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12
[SID103317043]
IC50 48Competitive inhibition of Epac2 using fluorescent nucleotide analog 8-NBD-cAMP by fluorescence analysis [AID663168, Type: Literature]
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13
[SID103317043]
Activation of olfactory CNG A2A41b channel expressed in HEK293 cells assessed as effect on half maximal current [AID297178, Type: Literature]
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14
[SID17404647]
Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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