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AGN-PC-0BISAT (CID 56846685) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(5)
 
 
BioAssay Types:
Confirmatory(5)
 
 
BioActivity Types:
IC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID135378310]
Average Hum18AAP IC50 8.36Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the human M18 Aspartyl Aminopeptidase (hM18AAP) (3) [AID624174, Type: confirmatory]
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2
[SID135378310]
Average PFM18AAP IC50 9.8QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (2) [AID624177, Type: confirmatory]
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3
[SID135378310]
Average PFM17LAP IC50 35.71Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID624175, Type: confirmatory]
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4
[SID135378310]
Avg CC50 50Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3) [AID624205, Type: confirmatory]
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5
[SID135378310]
Average PFM1AAP IC50 105.9Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3) [AID624176, Type: confirmatory]
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