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AGN-PC-09S583 (CID 53377400) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Top Targets:
ABC ATPase(2)
 
 
Rab7(2)
 
 
RhoA like(1)
 
 
BioAssay Types:
Confirmatory(4)
 
 
BioActivity Types:
EC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125299364]
EC50_MICROM 0.854SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically H-Ras activated mutant, round 2 [AID588628, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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2
[SID125299364]
EC50_MICROM 1.157SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype, round 2 [AID588631, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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3
[SID125299364]
EC50_MICROM 1.386SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically H-Ras wildtype, round 2 [AID588630, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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4
[SID125299364]
EC50_MICROM 5.869SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype, round 2 [AID588626, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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5
[SID125299364]
Dose Response of round 2 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer [AID588622, Type: other]
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6
[SID125299364]
Dose Response of round 2 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer [AID588622_1, Type: other]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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7
[SID125299364]
Dose Response of round 2 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer [AID588622_2, Type: other]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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8
[SID125299364]
Dose Response of round 2 SAR compounds for GTPase inhibitor project tested by multiplex of eight GTPase proteins under the condition of Mg Buffer, non-chelator buffer [AID588622_5, Type: other]GTPase [Homo sapiens] [gi:407699]
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