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Hydrocodone (CID 5284569) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(6)
 
 
Top Targets:
7TM GPCR Srx(2)
 
 
BioAssay Types:
Literature(5)
 
 
BioActivity Types:
Ki(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103526751]
Ki 0.0095Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID670110, Type: Literature]Mu-type opioid receptor [gi:2851402]
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2
[SID103526751]
Ki 0.26Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation counting [AID670111, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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3
[SID103526751]
ED50 2.4Analgesic activity was measured by acetic acid writhing test in mouse by giving subcutaneous injection [AID128495, Type: Literature]
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4
[SID103526751]
ED50 5.2Analgesic activity measured by rat tail flick assay following s.c. administration. [AID177776, Type: Literature]
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5
[SID103526751]
Metabolic stability in human liver microsomes assessed as GSH adduct formation at 100 uM after 90 mins by HPLC-MS analysis [AID678721, Type: Literature]
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6
[SID48416090]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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