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Calcifediol (CID 5283731) - Compound BioActivity Data
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Filters: All Data » Active      
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BioActivity Outcomes:
Active(32)
 
 
Top Targets:
NR LBD AR(3)
 
 
Geminin(1)
 
 
NR LBD ROR li..(1)
 
 
NR LBD TR(1)
 
 
BioAssay Types:
Literature(14)
 
 
Confirmatory(14)
 
 
Summary(3)
 
 
BioActivity Types:
Potency(17)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 32   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205540]
Potency-Replicate_1 5.308qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144205540]
Ratio Potency (uM) 5.81729qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID144205540]
Potency-Replicate_1 5.9557qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144205540]
Potency-Replicate_1 5.9557qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144205540]
Potency-Replicate_1 6.6824qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID144205540]
Potency-Replicate_1 6.6824qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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7
[SID50110817]
Potency 10.5931A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID144205540]
Potency-Replicate_1 10.6822qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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9
[SID50110817]
Potency 11.2202VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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10
[SID144205540]
Potency-Replicate_1 11.8832qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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11
[SID144205540]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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12
[SID144205540]
Potency 12.5893qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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13
[SID144205540]
Potency-Replicate_1 13.3332qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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14
[SID144205540]
Potency-Replicate_1 23.9145qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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15
[SID144205540]
Potency-Replicate_1 26.6032qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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16
[SID144205540]
Ratio Potency (uM) 26.8325qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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17
[SID144205540]
AR Potency (uM) 28.7255qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
18
[SID103279820]
Inhibition of Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as down regulation of Gli1 at 0.5 to 5 uM after 24 hrs by RT-PCR analysis [AID647370, Type: Literature]
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19
[SID48415681]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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20
[SID50110817]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_60, Type: Literature]
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