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Aspirin (CID 2244) - Compound BioActivity Data
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Filters: All Data » Ki      
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BioActivity Outcomes:
Unspecified(9)
 
 
Top Targets:
Lipocalin(2)
 
 
MFS(2)
 
 
alpha CA I II..(2)
 
 
prostaglandin..(2)
 
 
BioAssay Types:
Literature(9)
 
 
BioActivity Types:
Ki(9)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164874]
Ki 52Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method [AID1053267, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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2
[SID103164874]
Ki 62Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate assessed as formation of prostanoid products preincubated for 10 mins prior to substrate addition measured after 2 mins by Ellman's method [AID1053273, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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3
[SID103164874]
Ki 102.329Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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4
[SID103164874]
Ki 348Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by competitive fluorescence displacement assay [AID407366, Type: Literature]Fatty acid-binding protein, liver [gi:119810]
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5
[SID103164874]
Ki 691.831Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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6
[SID103164874]
Ki 3660Inhibition of human carbonic anhydrase 2 esterase activity by non-competitive Lineweaver-Burke plot [AID349145, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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7
[SID103164874]
Ki 3780Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP low binding affinity site expressed in Escherichia coli BL21 by competitive fluorescence displacement assay [AID407369, Type: Literature]Fatty acid-binding protein, liver [gi:119810]
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8
[SID103164874]
Ki 7530Inhibition of human carbonic anhydrase 1 esterase activity by noncompetitive Lineweaver-Burke plot [AID349142, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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9
[SID103164874]
Ki 20000Inhibition of cyclooxygenase [AID313117, Type: Literature]
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