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imatinib (CID 5291) - Compound BioActivity Data
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Filters: All Data » Kd      
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BioActivity Outcomes:
Active(116)
 
 
Inactive(96)
 
 
Unspecified(670)
 
 
Top Targets:
PKc(94)
 
 
 
 
PKc like(76)
 
 
 
 
STKc AGC(43)
 
 
 
 
PTKc Abl(34)
 
 
 
PTKc EGFR(23)
 
 
 
 
BioAssay Types:
Literature(882)
 
 
 
 
BioActivity Types:
Kd(882)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 882    Data Row: 882   Total Pages: 18   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103245522]
Kd 0.0007Binding constant for DDR1 kinase domain [AID435400, Type: Literature]Epithelial discoidin domain-containing receptor 1 [gi:729008]
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2
[SID103245522]
Kd 0.0007Binding constant for DDR1 kinase domain [AID624850, Type: Literature]Epithelial discoidin domain-containing receptor 1 [gi:729008]
View
3
[SID103245522]
Kd 0.0011Binding constant for ABL1-nonphosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
4
[SID103245522]
Kd 0.0018Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
5
[SID103245522]
Kd 0.0022Average Binding Constant for ABL1 ; NA=Not Active at 10 uM [AID256665, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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6
[SID103245522]
Kd 0.0025Binding constant for ABL1(F317L)-nonphosphorylated kinase domain [AID624981, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
7
[SID103245522]
Kd 0.0059Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
8
[SID103245522]
Kd 0.006Binding affinity to human active site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration calorimetric assay [AID593557, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
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9
[SID103245522]
Kd 0.0083Binding constant for ABL1(F317I)-nonphosphorylated kinase domain [AID624979, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID103245522]
Kd 0.0085Binding constant for ABL1(M351T) kinase domain [AID435514, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
11
[SID103245522]
Kd 0.01Binding constant for ABL2 kinase domain [AID435777, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
12
[SID103245522]
Kd 0.01Binding constant for ABL2 kinase domain [AID624993, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
13
[SID103245522]
Kd 0.011Binding constant for CSF1R kinase domain [AID624995, Type: Literature]Macrophage colony-stimulating factor 1 receptor [gi:547770]
View
14
[SID103245522]
Kd 0.012Binding constant for ABL1 kinase domain [AID435775, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
15
[SID103245522]
Kd 0.013Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
16
[SID103245522]
Kd 0.013Average Binding Constant for ABL2 ; NA=Not Active at 10 uM [AID256641, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
17
[SID103245522]
Kd 0.014Binding constant for KIT kinase domain [AID435410, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
18
[SID103245522]
Kd 0.014Average Binding Constant for ABL1(M351T) ; NA=Not Active at 10 uM [AID256669, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID103245522]
Kd 0.014Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
20
[SID103245522]
Kd 0.014Binding constant for PDGFRB kinase domain [AID624875, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
21
[SID103245522]
Kd 0.014Binding constant for PDGFRB kinase domain [AID435926, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
22
[SID103245522]
Kd 0.014Binding affinity to human KIT incubated for 1 hr by kinase binding assay [AID599957, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
23
[SID103245522]
Kd 0.015Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
24
[SID103245522]
Kd 0.015Binding constant for KIT(A829P) kinase domain [AID624787, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
25
[SID103245522]
Kd 0.015Binding constant for DDR2 kinase domain [AID624777, Type: Literature]Discoidin domain-containing receptor 2 [gi:215273969]
View
26
[SID103245522]
Kd 0.015Binding constant for DDR2 kinase domain [AID435154, Type: Literature]Discoidin domain-containing receptor 2 [gi:215273969]
View
27
[SID103245522]
Kd 0.015Binding constant for KIT(V559D) kinase domain [AID435167, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
28
[SID103245522]
Kd 0.019Binding constant for CSF1R kinase domain [AID435280, Type: Literature]Macrophage colony-stimulating factor 1 receptor [gi:547770]
View
29
[SID103245522]
Kd 0.021Binding constant for ABL1(Q252H) kinase domain [AID435515, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
30
[SID103245522]
Kd 0.021Binding constant for ABL1-phosphorylated kinase domain [AID624992, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
31
[SID103245522]
Kd 0.024Average Binding Constant for ABL1(Q252H) ; NA=Not Active at 10 uM [AID256666, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
32
[SID103245522]
Kd 0.028Average Binding Constant for PDGFRB ; NA=Not Active at 10 uM [AID256661, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
33
[SID103245522]
Kd 0.031Binding constant for PDGFRA kinase domain [AID435827, Type: Literature]Platelet-derived growth factor receptor alpha [gi:129892]
View
34
[SID103245522]
Kd 0.031Binding constant for PDGFRA kinase domain [AID625034, Type: Literature]Platelet-derived growth factor receptor alpha [gi:129892]
View
35
[SID103245522]
Kd 0.035Binding constant for ABL1(H396P) kinase domain [AID435146, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
36
[SID103245522]
Kd 0.04Binding constant for LCK kinase domain [AID435676, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
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37
[SID103245522]
Kd 0.04Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
38
[SID103245522]
Kd 0.044Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
39
[SID103245522]
Kd 0.044Average Binding Constant for ABL1(Y253F) ; NA=Not Active at 10 uM [AID256671, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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40
[SID103245522]
Kd 0.044Binding constant for ABL1(Y253F) kinase domain [AID435776, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
41
[SID103245522]
Kd 0.062Average Binding Constant for LCK ; NA=Not Active at 10 uM [AID256657, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
42
[SID103245522]
Kd 0.062Average Binding Constant for ABL1(H396P) ; NA=Not Active at 10 uM [AID256668, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
43
[SID103245522]
Kd 0.065Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
44
[SID103245522]
Kd 0.071Binding constant for KIT(V559D,V654A) kinase domain [AID435802, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
45
[SID103245522]
Kd 0.077Binding constant for ABL1(E255K) kinase domain [AID435644, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
46
[SID103245522]
Kd 0.091Binding constant for KIT(V559D,V654A) kinase domain [AID624793, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
47
[SID103245522]
Kd 0.092Binding constant for ABL1(Q252H)-phosphorylated kinase domain [AID624987, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
48
[SID103245522]
Kd 0.11Binding constant for ABL1(F317L)-phosphorylated kinase domain [AID624982, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
49
[SID103245522]
Kd 0.11Average Binding Constant for ABL1(E255K) ; NA=Not Active at 10 uM [AID256667, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
50
[SID103245522]
Kd 0.13Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View