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imatinib (CID 5291) - Compound BioActivity Data
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Filters: All Data » Kd      
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BioActivity Outcomes:
Active(116)
 
 
Inactive(96)
 
 
Unspecified(670)
 
 
Top Targets:
PTKc Abl(34)
 
 
 
PTKc EGFR(23)
 
 
 
 
STKc RSK N(16)
 
 
 
PTKc EphR A(15)
 
 
 
 
PTKc Kit(15)
 
 
BioAssay Types:
Literature(882)
 
 
 
 
BioActivity Types:
Kd(882)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 882    Data Row: 882   Total Pages: 45   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103245522]
Kd 0.0007Binding constant for DDR1 kinase domain [AID435400, Type: Literature]Epithelial discoidin domain-containing receptor 1 [gi:729008]
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2
[SID103245522]
Kd 0.0007Binding constant for DDR1 kinase domain [AID624850, Type: Literature]Epithelial discoidin domain-containing receptor 1 [gi:729008]
View
3
[SID103245522]
Kd 0.0011Binding constant for ABL1-non phosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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4
[SID103245522]
Kd 0.0018Binding constant for ABL1(Q252H)-non phosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
5
[SID103245522]
Kd 0.0022Average Binding Constant for ABL1; NA=Not Active at 10 uM [AID256665, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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6
[SID103245522]
Kd 0.0025Binding constant for ABL1(F317L)-non phosphorylated kinase domain [AID624981, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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7
[SID103245522]
Kd 0.0059Binding constant for ABL1(H396P)-non phosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
8
[SID103245522]
Kd 0.006Binding affinity to human active site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration calorimetric assay [AID593557, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
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9
[SID103245522]
Kd 0.0083Binding constant for ABL1(F317I)-non phosphorylated kinase domain [AID624979, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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10
[SID103245522]
Kd 0.0085Binding constant for ABL1(M351T) kinase domain [AID435514, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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11
[SID103245522]
Kd 0.01Binding constant for ABL2 kinase domain [AID435777, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
12
[SID103245522]
Kd 0.01Binding constant for ABL2 kinase domain [AID624993, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
13
[SID103245522]
Kd 0.011Binding constant for CSF1R kinase domain [AID624995, Type: Literature]Macrophage colony-stimulating factor 1 receptor [gi:547770]
View
14
[SID103245522]
Kd 0.012Binding constant for ABL1 kinase domain [AID435775, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
15
[SID103245522]
Kd 0.013Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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16
[SID103245522]
Kd 0.013Average Binding Constant for ABL2; NA=Not Active at 10 uM [AID256641, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
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17
[SID103245522]
Kd 0.014Binding constant for KIT kinase domain [AID435410, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
18
[SID103245522]
Kd 0.014Average Binding Constant for ABL1(M351T); NA=Not Active at 10 uM [AID256669, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID103245522]
Kd 0.014Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
20
[SID103245522]
Kd 0.014Binding constant for PDGFRB kinase domain [AID624875, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View