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hydrazine (CID 9321) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Unspecified(116)
 
 
Top Targets:
7TM GPCR Srsx(15)
 
 
7TM GPCR Srx(15)
 
 
p450(7)
 
 
prostaglandin..(2)
 
 
STKc ERK1 2 l..(2)
 
 
BioAssay Types:
Confirmatory(116)
 
 
BioActivity Types:
IC50(116)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 116    Data Row: 116   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123092331]
IC50 DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) [AID625202, Type: confirmatory]Alpha-2B adrenergic receptor [gi:613504690]
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2
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625151, Type: confirmatory]Muscarinic acetylcholine receptor M1 [gi:113118]
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3
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625152, Type: confirmatory]Muscarinic acetylcholine receptor M2 [gi:113122]
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4
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625153, Type: confirmatory]Muscarinic acetylcholine receptor M3 [gi:113125]
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5
[SID123092331]
IC50 DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: confirmatory]Androgen receptor [gi:113832]
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6
[SID123092331]
IC50 DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) [AID625150, Type: confirmatory]Amine oxidase [flavin-containing] A [gi:113978]
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7
[SID123092331]
IC50 DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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8
[SID123092331]
IC50 DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) [AID625238, Type: confirmatory]C-C chemokine receptor type 4 [gi:1705894]
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9
[SID123092331]
IC50 DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) [AID625239, Type: confirmatory]C-C chemokine receptor type 5 [gi:1705896]
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10
[SID123092331]
IC50 DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) [AID625244, Type: confirmatory]Prostaglandin G/H synthase 2 [gi:3915797]
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11
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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12
[SID123092331]
IC50 DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) [AID625171, Type: confirmatory]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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13
[SID123092331]
IC50 DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) [AID625204, Type: confirmatory]Beta-1 adrenergic receptor [gi:48429211]
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14
[SID123092331]
IC50 DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) [AID625172, Type: confirmatory]Progesterone receptor [gi:75071465]
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15
[SID123092331]
IC50 DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) [AID625161, Type: confirmatory]Delta-type opioid receptor [gi:311033488]
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16
[SID123092331]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) [AID625191, Type: confirmatory]5-hydroxytryptamine receptor 1B [gi:112815]
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17
[SID123092331]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) [AID625218, Type: confirmatory]5-hydroxytryptamine receptor 2C [gi:112816]
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18
[SID123092331]
IC50 DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) [AID625193, Type: confirmatory]Acetylcholinesterase [gi:113037]
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19
[SID123092331]
IC50 DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) [AID625236, Type: confirmatory]Carbonic anhydrase 2 [gi:115456]
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20
[SID123092331]
IC50 DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) [AID625235, Type: confirmatory]Cannabinoid receptor 1 [gi:115562]
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