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hydrazine (CID 9321) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Unspecified(116)
 
 
Top Targets:
7TM GPCR Srx(16)
 
 
7TM GPCR Srsx(15)
 
 
p450(7)
 
 
prostaglandin..(2)
 
 
STKc ERK1 2 l..(2)
 
 
BioAssay Types:
Confirmatory(116)
 
 
BioActivity Types:
IC50(116)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 116    Data Row: 116   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123092331]
IC50 DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) [AID625144, Type: confirmatory]Leukotriene C4 synthase [gi:239977155]
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2
[SID123092331]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: confirmatory]Cysteinyl leukotriene receptor 1 [gi:20138087]
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3
[SID123092331]
IC50 DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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4
[SID123092331]
IC50 DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625147, Type: confirmatory]Melanocortin receptor 3 [gi:395398606]
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5
[SID123092331]
IC50 DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625148, Type: confirmatory]Melanocortin receptor 4 [gi:60392672]
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6
[SID123092331]
IC50 DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625149, Type: confirmatory]Melanocortin receptor 5 [gi:729996]
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7
[SID123092331]
IC50 DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) [AID625150, Type: confirmatory]Amine oxidase [flavin-containing] A [gi:113978]
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8
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625151, Type: confirmatory]Muscarinic acetylcholine receptor M1 [gi:113118]
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9
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625152, Type: confirmatory]Muscarinic acetylcholine receptor M2 [gi:113122]
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10
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625153, Type: confirmatory]Muscarinic acetylcholine receptor M3 [gi:113125]
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11
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625154, Type: confirmatory]Muscarinic acetylcholine receptor M4 [gi:23503039]
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12
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625155, Type: confirmatory]Muscarinic acetylcholine receptor M5 [gi:543761]
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13
[SID123092331]
IC50 DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) [AID625157, Type: confirmatory]Neuropeptide Y receptor type 2 [gi:1352610]
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14
[SID123092331]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: confirmatory]
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15
[SID123092331]
IC50 DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) [AID625159, Type: confirmatory]Nitric oxide synthase, brain [gi:266646]
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16
[SID123092331]
IC50 DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) [AID625161, Type: confirmatory]Delta-type opioid receptor [gi:311033488]
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17
[SID123092331]
IC50 DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625162, Type: confirmatory]Kappa-type opioid receptor [gi:116242691]
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18
[SID123092331]
IC50 DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625163, Type: confirmatory]Mu-type opioid receptor [gi:2851402]
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19
[SID123092331]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
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20
[SID123092331]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: confirmatory]
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