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hydrazine (CID 9321) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Unspecified(116)
 
 
Top Targets:
7tm 4(30)
 
 
p450(7)
 
 
prostaglandin..(2)
 
 
STKc ERK1 2 l..(2)
 
 
NR LBD ER(2)
 
 
BioAssay Types:
Confirmatory(116)
 
 
BioActivity Types:
IC50(116)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 116    Data Row: 116   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123092331]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) [AID625191, Type: confirmatory]5-hydroxytryptamine receptor 1B [gi:112815]
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2
[SID123092331]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) [AID625218, Type: confirmatory]5-hydroxytryptamine receptor 2C [gi:112816]
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3
[SID123092331]
IC50 DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) [AID625193, Type: confirmatory]Acetylcholinesterase [gi:113037]
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4
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625151, Type: confirmatory]Muscarinic acetylcholine receptor M1 [gi:113118]
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5
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625152, Type: confirmatory]Muscarinic acetylcholine receptor M2 [gi:113122]
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6
[SID123092331]
IC50 DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625153, Type: confirmatory]Muscarinic acetylcholine receptor M3 [gi:113125]
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7
[SID123092331]
IC50 DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) [AID625228, Type: confirmatory]Androgen receptor [gi:113832]
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8
[SID123092331]
IC50 DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) [AID625150, Type: confirmatory]Amine oxidase [flavin-containing] A [gi:113978]
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9
[SID123092331]
IC50 DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) [AID625236, Type: confirmatory]Carbonic anhydrase 2 [gi:115456]
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10
[SID123092331]
IC50 DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) [AID625235, Type: confirmatory]Cannabinoid receptor 1 [gi:115562]
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11
[SID123092331]
IC50 DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) [AID625175, Type: confirmatory]Cathepsin G [gi:115725]
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12
[SID123092331]
IC50 DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) [AID625177, Type: confirmatory]Interstitial collagenase [gi:116852]
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13
[SID123092331]
IC50 DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625245, Type: confirmatory]Cytochrome P450 1A2 [gi:117144]
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14
[SID123092331]
IC50 DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625250, Type: confirmatory]Cytochrome P450 2E1 [gi:117250]
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15
[SID123092331]
IC50 DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) [AID625253, Type: confirmatory]D(2) dopamine receptor [gi:118206]
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16
[SID123092331]
IC50 DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) [AID625252, Type: confirmatory]D(1A) dopamine receptor [gi:118228]
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17
[SID123092331]
IC50 DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625186, Type: confirmatory]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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18
[SID123092331]
IC50 DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) [AID625181, Type: confirmatory]Mitogen-activated protein kinase 1 [gi:119554]
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19
[SID123092331]
IC50 DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) [AID625257, Type: confirmatory]Endothelin-1 receptor [gi:119606]
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20
[SID123092331]
IC50 DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) [AID625263, Type: confirmatory]Glucocorticoid receptor [gi:121069]
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