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Catechin (CID 9064) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Active(12)
 
 
Inactive(2)
 
 
Inconclusive(1)
 
 
Unspecified(19)
 
 
Top Targets:
prostaglandin..(7)
 
 
 
Aldo ket red(1)
 
 
CAP ED(1)
 
 
BioAssay Types:
Literature(33)
 
 
 
 
 
Confirmatory(1)
 
 
BioActivity Types:
IC50(34)
 
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 34    Data Row: 34   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123094711]
IC50 1.61Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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2
[SID123094711]
IC50 2.31Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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3
[SID123094711]
IC50 2.9Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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4
[SID123094711]
IC50 4.1Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay [AID333439, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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5
[SID123094711]
IC50 4.3Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry [AID650645, Type: Literature]
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6
[SID123094711]
IC50 5.3Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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7
[SID123094711]
IC50 13.1Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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8
[SID123094711]
IC50 20.2Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay [AID333440, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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9
[SID123094711]
IC50 20.2Free radical scavenging activity of DPPH was determined; value taken from reference 11 [AID226690, Type: Literature]
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10
[SID123094711]
IC50 21.1Inhibition of Saccharomyces cerevisiae alcohol dehydrogenase measured every 5 mins for 2 hrs by spectrophotometry [AID650644, Type: Literature]
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11
[SID123094711]
IC50 36.7Inhibition of COX1 [AID332217, Type: Literature]
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12
[SID123094711]
IC50 49Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356646, Type: Literature]
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13
[SID123094711]
IC50 30Inhibition of aldose reductase in rat lens homogenate [AID356411, Type: Literature]Aldose reductase [gi:1168407]
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14
[SID123094711]
IC50 80Inhibition of bovine seminal vesicle microsomal COX1-mediated prostaglandin production [AID399411, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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15
[SID123094711]
IC50 80Inhibition of COX1 [AID403341, Type: Literature]
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16
[SID123094711]
IC50 93.3Inhibition of COX2 [AID332218, Type: Literature]
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17
[SID123094711]
IC50 100Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
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18
[SID123094711]
IC50 130Inhibition of COX2 [AID403340, Type: Literature]
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19
[SID123094711]
IC50 144Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 [AID265761, Type: Literature]
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20
[SID123094711]
IC50 183Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production [AID399401, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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21
[SID123094711]
IC50 279Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 mins [AID399404, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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22
[SID123094711]
IC50 345Cytotoxicity against human H9 cells after 3 days [AID332930, Type: Literature]
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23
[SID123094711]
IC50 546Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production [AID399402, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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24
[SID123094711]
IC50 647.2Modulation of classical complement pathway system assessed as hemoglobin release by spectrophotometry [AID380219, Type: Literature]
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25
[SID123094711]
IC50 5910Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 mins [AID399405, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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26
[SID123094711]
IC50 Inhibition of Hepatitic C virus NS3/4A protease by FRET assay [AID641102, Type: Literature]
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27
[SID123094711]
IC50 Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay [AID379520, Type: Literature]
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28
[SID123094711]
IC50 Cytotoxicity against human A549 cells after 96 hrs by MTT assay [AID379516, Type: Literature]
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29
[SID123094711]
IC50 Cytotoxicity against human A2780 cells after 96 hrs by MTT assay [AID379517, Type: Literature]
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30
[SID123094711]
IC50 Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay [AID379518, Type: Literature]
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31
[SID123094711]
IC50 Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay [AID379519, Type: Literature]
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32
[SID123094711]
IC50 Modulation of alternative complement pathway system assessed as hemoglobin release by spectrophotometry [AID380220, Type: Literature]
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33
[SID49698653]
IC50 Vibrio cholerae assay for pro-quorum sensing small molecules [AID686977, Type: confirmatory]cyclic AMP receptor protein [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657203]
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34
[SID123094711]
IC50 Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 [AID265762, Type: Literature]
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