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BioActivity Data for Compound 2-Anilino-1,4-naphthoquinone (CID 81124)

Filters: All Data » IC50      
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BioActivity Outcomes:
Active(5)
 
 
Inactive(38)
 
 
Inconclusive(3)
 
 
Unspecified(1)
 
 
Top Targets:
PMI typeI(2)
 
 
 
Vif(1)
 
 
Uba2 SUMO(1)
 
 
UBCc(1)
 
 
Runt(1)
 
 
BioAssay Types:
Confirmatory(44)
 
 
 
 
Literature(3)
 
 
 
BioAssay Categories:
Biochemical(1)
 
 
Cell-based(8)
 
 
 
 
Toxicity(3)
 
 
 
BioActivity Types:
IC50(47)
 
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 42    Data Row: 47   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103284973]
IC50 5.52Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763580, Type: Literature]
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2
[SID24824101]
IC50 11.694High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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3
[SID103284973]
IC50 31.25Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763578, Type: Literature]
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4
[SID24824101]
IC50 81.685Discovery of Small Molecule Probes for H1N1 Influenza NS1A [AID504329, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/California/07/2009(H1N1))] [gi:227977143]
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5
[SID24824101]
IC50 HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate [AID1220, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
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6
[SID103284973]
IC50 100Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763579, Type: Literature]
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7
[SID24824101]
IC50 6.1627Dose Response Confirmation for Calpain Inhibitors [AID1420, Type: confirmatory]calpain II, partial [Sus scrofa] [gi:1628587]
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8
[SID24824101]
IC50 Image-Based HTS for Selective Antagonists of GPR35 [AID2058, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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9
[SID24824101]
Average IC50 High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G:#A time-resolved fluorescence resonance energy transfer (TR-FRET) assay for HIV-1 Vif-APOBEC3G interaction [AID1117319, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
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10
[SID24824101]
Average IC50 High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G:#A time-resolved fluorescence resonance energy transfer (TR-FRET) assay for HIV-1 Vif-APOBEC3G interaction [AID1117319, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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11
[SID24824101]
IC50 HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. [AID1209, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
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12
[SID24824101]
IC50 Chemical Antagonists IAP-family anti-apoptotic proteins [AID1018, Type: confirmatory]X-linked inhibitor of apoptosis [Homo sapiens] [gi:8744934]
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13
[SID24824101]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
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14
[SID24824101]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) [AID2012, Type: confirmatory]Eukaryotic translation initiation factor 4H [Homo sapiens] [gi:45219878]
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15
[SID24824101]
IC50 Image-Based HTS for Selective Antagonists for GPR55 [AID2013, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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16
[SID24824101]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) [AID2014, Type: confirmatory]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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17
[SID24824101]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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18
[SID24824101]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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19
[SID24824101]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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20
[SID24824101]
IC50 uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
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