Bookmark and Share
Dopamine (CID 681) - Compound BioActivity Data
.
Filters: All Data » IC50      
Filter selected
BioActivity Outcomes:
Active(48)
 
 
Inconclusive(16)
 
 
Unspecified(11)
 
 
Top Targets:
7tm 4(19)
 
 
MFS(4)
 
 
Herpes DNAp a..(2)
 
 
SLC6sbd DAT1(2)
 
 
SLC6sbd NET(1)
 
 
BioAssay Types:
Literature(64)
 
 
 
 
Confirmatory(11)
 
 
 
BioActivity Types:
IC50(75)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 65    Data Row: 75   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167911]
IC50 8e-09Agonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]-Spiperone [AID62635, Type: Literature]
View
2
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(1B) dopamine receptor [gi:118251]
View
3
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(3) dopamine receptor [gi:118211]
View
4
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(4) dopamine receptor [gi:6226851]
View
5
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(1A) dopamine receptor [gi:118229]
View
6
[SID103167911]
IC50 0.002Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN [AID196429, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
7
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(4) dopamine receptor [gi:6226851]
View
8
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(1A) dopamine receptor [gi:118229]
View
9
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(1B) dopamine receptor [gi:118251]
View
10
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(3) dopamine receptor [gi:118211]
View
11
[SID103167911]
IC50 0.0021Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride [AID196428, Type: Literature]D(2) dopamine receptor [gi:47117674]
View
12
[SID103167911]
IC50 0.0037Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates. [AID62451, Type: Literature]
View
13
[SID103167911]
IC50 0.0045Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates. [AID62452, Type: Literature]
View
14
[SID103167911]
IC50 0.00663Inhibition of [3H]norepinephrine uptake in HEK cells expressing human NET [AID145556, Type: Literature]Sodium-dependent noradrenaline transporter [gi:128616]
View
15
[SID103167911]
IC50 0.015The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each performed in triplicate. [AID62573, Type: Literature]
View
16
[SID103167911]
IC50 0.029Compound concentration required to reduce specific binding of tritiated dopamine to rat brain striatal membrane by 50 % was reported [AID195878, Type: Literature]
View
17
[SID103167911]
IC50 0.061Concentration that produces 50 % displacement of specific [3H]clonidine binding to Alpha adrenergic receptor in rat brain cortical membrane preparations. [AID33127, Type: Literature]
View
18
[SID103167911]
IC50 0.064Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei. [AID62445, Type: Literature]
View
19
[SID103167911]
IC50 0.111Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting [AID1093077, Type: confirmatory]D(3) dopamine receptor [gi:118211]
View
20
[SID103167911]
IC50 0.124Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cells after 1 hr by beta scintillation counting [AID1093078, Type: confirmatory]D(3) dopamine receptor [gi:118211]
View