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Tryptophan (CID 6305) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Active(8)
 
 
Inactive(26)
 
 
Unspecified(6)
 
 
Top Targets:
Uba2 SUMO(1)
 
 
UBCc(1)
 
 
Runt(1)
 
 
RRM eIF4H(1)
 
 
RRM1 I PABPs(1)
 
 
BioAssay Types:
Confirmatory(26)
 
 
Literature(14)
 
 
 
BioActivity Types:
IC50(40)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 36    Data Row: 40   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103241616]
IC50 3.5Antioxidant activity assessed as inhibition of HOCl-induced oxidation of DHR by rhodamine 123 staining [AID537676, Type: Literature]
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2
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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3
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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4
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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5
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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6
[SID103241616]
IC50 19.2Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in presence of NaHCO3 [AID537680, Type: Literature]
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7
[SID103241616]
IC50 31.9Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in absence of NaHCO3 [AID537679, Type: Literature]
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8
[SID103241616]
IC50 Inhibition of human recombinant KAT1 expressed in Sf9 cells [AID349604, Type: Literature]Kynurenine--oxoglutarate transaminase 1 [gi:46396284]
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9
[SID103241616]
IC50 5Inhibition of PLAP by analogous luminescence assay [AID459064, Type: Literature]
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10
[SID103241616]
IC50 5Inhibition of TNAP by analogous luminescence assay [AID459065, Type: Literature]
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11
[SID103241616]
IC50 5Inhibition of IAP by analogous luminescence assay [AID459066, Type: Literature]
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12
[SID103241616]
IC50 500In vitro inhibition of recombinant stromelysin catalytic domain. [AID208197, Type: Literature]
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13
[SID103241616]
IC50 992Antioxidant activity assessed as inhibition of singlet oxygen-induced oxidation of DHR by rhodamine 123 staining [AID537677, Type: Literature]
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14
[SID103241616]
IC50 1151Antioxidant activity assessed as inhibition of nitric oxide-induced oxidation of non-fluorescent DAF-2 by fluorescence assay [AID537678, Type: Literature]
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15
[SID26732620]
IC50 uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
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16
[SID26732620]
IC50 Fluorescence for the identification of compounds that decrease p/CIP protein stability [AID1984, Type: confirmatory]nuclear receptor coactivator 3 [Mus musculus] [gi:118026946]
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17
[SID26732620]
IC50 Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) [AID1445, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:124512980]
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18
[SID26732620]
IC50 Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) [AID1619, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:124809582]
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19
[SID26732620]
IC50 uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1 [AID1565, Type: confirmatory]phosphoethanolamine/phosphocholine phosphatase isoform 1 [Homo sapiens] [gi:219689097]
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20
[SID26732620]
IC50 uHTS identification of small molecule inhibitors of LYP via a fluorescence intensity assay [AID1779, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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21
[SID26732620]
IC50 A Cell Based Assay for the Identification of Lead Compounds with Anti-Viral Activity Against West Nile Virus [AID1621, Type: confirmatory]
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22
[SID26732620]
IC50 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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23
[SID26732620]
IC50 HCS for Compounds that Down-Regulate Insulin Promoter Activity in MIN6 Cells [AID1628, Type: confirmatory]
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24
[SID26732620]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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25
[SID26732620]
IC50 Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2073, Type: confirmatory]Mint1 [Rattus norvegicus] [gi:2625023]
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26
[SID26732620]
IC50 Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2073, Type: confirmatory]voltage-dependent N-type calcium channel subunit alpha-1B isoform 1 [Homo sapiens] [gi:4502523]
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27
[SID26732620]
IC50_Mean High Throughput Imaging Assay for Beta-Catenin [AID1665, Type: confirmatory]catenin beta-1 [Homo sapiens] [gi:4503131]
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28
[SID26732620]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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29
[SID26732620]
IC50 uHTS absorbance assay for the identification of compounds that inhibit VHR1. [AID1654, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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30
[SID26732620]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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31
[SID26732620]
IC50 uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. [AID1434, Type: confirmatory]core-binding factor subunit beta isoform 1 [Homo sapiens] [gi:13124881]
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32
[SID26732620]
IC50 Inhibitors of Mycobacterial Glucosamine-1-phosphate acetyl transferase (GlmU) [AID1376, Type: confirmatory]Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU [Mycobacterium tuberculosis H37Rv] [gi:15608158]
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33
[SID26732620]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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34
[SID26732620]
IC50 uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. [AID1434, Type: confirmatory]runt-related transcription factor 1 isoform AML1c [Homo sapiens] [gi:19923198]
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35
[SID26732620]
IC50 Image-Based HTS for Selective Antagonists of GPR35 [AID2058, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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36
[SID26732620]
IC50 Image-Based HTS for Selective Antagonists for GPR55 [AID2013, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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37
[SID26732620]
IC50 uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay [AID1778, Type: confirmatory]kappa-type opioid receptor isoform 1 [Homo sapiens] [gi:39725940]
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38
[SID26732620]
IC50 uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay. [AID1817, Type: confirmatory]plectin 1 [Homo sapiens] [gi:40849930]
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39
[SID26732620]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) [AID2012, Type: confirmatory]Eukaryotic translation initiation factor 4H [Homo sapiens] [gi:45219878]
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40
[SID26732620]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) [AID2014, Type: confirmatory]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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