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BioActivity Data for Compound Tryptophan (CID 6305)

Filters: All Data » IC50      
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BioActivity Outcomes:
Active(8)
 
 
Inactive(30)
 
 
Unspecified(6)
 
 
Top Targets:
Vif(1)
 
 
Uba2 SUMO(1)
 
 
UBCc(1)
 
 
Runt(1)
 
 
RRM eIF4H(1)
 
 
BioAssay Types:
Confirmatory(30)
 
 
Literature(14)
 
 
 
BioAssay Categories:
Biochemical(5)
 
 
 
Cell-based(2)
 
 
 
In vitro(2)
 
 
 
BioActivity Types:
IC50(44)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 39    Data Row: 44   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103241616]
IC50 3.5Antioxidant activity assessed as inhibition of HOCl-induced oxidation of DHR by rhodamine 123 staining [AID537676, Type: Literature]
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2
[SID103241616]
IC50 12.5893Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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3
[SID103241616]
IC50 12.5893Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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4
[SID103241616]
IC50 12.5893Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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5
[SID103241616]
IC50 12.5893Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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6
[SID103241616]
IC50 19.2Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in presence of NaHCO3 [AID537680, Type: Literature]
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7
[SID103241616]
IC50 31.9Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in absence of NaHCO3 [AID537679, Type: Literature]
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8
[SID103241616]
IC50 Inhibition of human recombinant KAT1 expressed in Sf9 cells [AID349604, Type: Literature]Kynurenine--oxoglutarate transaminase 1 [gi:46396284]
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9
[SID103241616]
IC50 5Inhibition of PLAP by analogous luminescence assay [AID459064, Type: Literature]
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10
[SID103241616]
IC50 5Inhibition of TNAP by analogous luminescence assay [AID459065, Type: Literature]
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11
[SID103241616]
IC50 5Inhibition of IAP by analogous luminescence assay [AID459066, Type: Literature]
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12
[SID103241616]
IC50 500In vitro inhibition of recombinant stromelysin catalytic domain. [AID208197, Type: Literature]
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13
[SID103241616]
IC50 992Antioxidant activity assessed as inhibition of singlet oxygen-induced oxidation of DHR by rhodamine 123 staining [AID537677, Type: Literature]
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14
[SID103241616]
IC50 1151Antioxidant activity assessed as inhibition of nitric oxide-induced oxidation of non-fluorescent DAF-2 by fluorescence assay [AID537678, Type: Literature]
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15
[SID26732620]
Average IC50 High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G:#A time-resolved fluorescence resonance energy transfer (TR-FRET) assay for HIV-1 Vif-APOBEC3G interaction [AID1117319, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
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16
[SID26732620]
Average IC50 High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G:#A time-resolved fluorescence resonance energy transfer (TR-FRET) assay for HIV-1 Vif-APOBEC3G interaction [AID1117319, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
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17
[SID26732620]
Average IC50 An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G [AID1117361, Type: confirmatory]Tat [Human immunodeficiency virus 1] [gi:9629358]
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18
[SID26732620]
Average IC50 A TR-FRET Counter Screen assay to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G [AID1117362, Type: confirmatory]glutathione-S-transferase [Schistosoma japonicum] [gi:1389744]
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19
[SID26732620]
IC50 Inhibitors of Mycobacterial Glucosamine-1-phosphate acetyl transferase (GlmU) [AID1376, Type: confirmatory]bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase [Mycobacterium tuberculosis H37Rv] [gi:15608158]
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20
[SID26732620]
IC50 uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. [AID1434, Type: confirmatory]runt-related transcription factor 1 isoform AML1c [Homo sapiens] [gi:19923198]
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