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Adenosine Diphosphate (CID 6022) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Active(7)
 
 
Unspecified(6)
 
 
Top Targets:
HSP90(3)
 
 
 
KISc BimC Eg5(2)
 
 
ACCA(1)
 
 
BioAssay Types:
Literature(13)
 
 
 
BioActivity Types:
IC50(13)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 13   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46393675]
IC50 0.45Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of Ksp In Complex With Inhibitor 1 [gi:66361184]
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2
[SID46393675]
IC50 0.45Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of Ksp In Complex With Inhibitor 1 [gi:66361184]
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3
[SID103176960]
IC50 0.5Displacement of fluorescein labeled N6-(6-amino)hexyl-ATP-5-FAM from HSP70 by fluorescence polarization assay [AID393506, Type: Literature]
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4
[SID103176960]
IC50 11.447Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from dog Grp94 after 24 hrs by fluorescence polarization assay [AID767752, Type: Literature]Endoplasmin [gi:729425]
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5
[SID103176960]
IC50 21Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis [AID751207, Type: Literature]
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6
[SID103176960]
IC50 30Antioxidant activity assessed as free radical scavenging activity after 7 mins by ABTS radical cation decolorization assay [AID751209, Type: Literature]
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7
[SID103176960]
IC50 42.159Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from recombinant HSP90beta (unknown origin) after 24 hrs by fluorescence polarization assay [AID767753, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
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8
[SID103176960]
IC50 19GRAC: human TRPM4 blocker [AID540551, Type: Literature]Transient receptor potential cation channel subfamily M member 4 [gi:74715868]
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9
[SID103176960]
IC50 55.594Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from recombinant human Trap-1 after 24 hrs by fluorescence polarization assay [AID767751, Type: Literature]Heat shock protein 75 kDa, mitochondrial [gi:67477458]
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10
[SID103176960]
IC50 59.308Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid from HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assay [AID767754, Type: Literature]Heat shock protein HSP 90-alpha [gi:92090606]
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11
[SID103176960]
IC50 145.3Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding site [AID155650, Type: Literature]
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12
[SID103176960]
IC50 170Antioxidant activity assessed as inhibiton of Fe2+-induced Fenton reaction-mediated hydroxyl radical formation from H2O2 measured for 150 secs by ESR analysis in presence of DMPO [AID751210, Type: Literature]
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13
[SID103176960]
IC50 400Binding affinity to HSP90 by fluorescence polarization assay [AID393511, Type: Literature]
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