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Rutin (CID 5280805) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Active(16)
 
 
Inactive(33)
 
 
Inconclusive(1)
 
 
Unspecified(10)
 
 
Top Targets:
Polyoma lg T..(2)
 
 
 
PMI typeI(2)
 
 
 
Uba2 SUMO(1)
 
 
UBCc(1)
 
 
Sialidase(1)
 
 
BioAssay Types:
Confirmatory(36)
 
 
 
 
Literature(24)
 
 
 
 
BioActivity Types:
IC50(60)
 
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 53    Data Row: 60   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103516775]
IC50 1.17Antioxidant activity assessed as nitric oxide scavenging activity by fluorescent triazofluorescein formation assay [AID453282, Type: Literature]
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2
[SID103516775]
IC50 2.53Antioxidant activity assessed as nitric oxide scavenging activity by spectrophotometry [AID515378, Type: Literature]
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3
[SID103516775]
IC50 3.66Nitric oxide scavenging activity assessed as inhibition of DAF2 oxidation [AID289333, Type: Literature]
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4
[SID103516775]
IC50 10.6Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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5
[SID103516775]
IC50 12.3Antioxidant activity assessed as DPPH radical scavenging activity [AID333567, Type: Literature]
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6
[SID103516775]
IC50 12.34Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356577, Type: Literature]
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7
[SID103516775]
IC50 13Inhibition of aldose reductase in rat lens homogenates by fluorophotometer [AID335838, Type: Literature]Aldose reductase [gi:1168407]
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8
[SID103516775]
IC50 30.9Inhibition of Clostridium perfringens neuraminidase [AID455702, Type: Literature]Sialidase [gi:127825]
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9
[SID103516775]
IC50 34.4Noncompetitive inhibition of recombinant influenza A virus rvH1N1 A/Bervig_Mission/1/18 neuraminidase [AID455703, Type: Literature]
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10
[SID103516775]
IC50 38.7Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by microplate reader [AID736009, Type: Literature]
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11
[SID103516775]
IC50 41.9Inhibition of glycation of bovine serum albumin assessed as advanced glycated end product measured after 7 days by spectrofluorimeter in presence of glucose anhydrous [AID721628, Type: Literature]Serum albumin [gi:1351907]
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12
[SID103516775]
IC50 41.9Antiglycation activity of compound assessed as inhibition of BSA-derived advance glycated end product formation after 7 days by spectrofluorimeter [AID395278, Type: Literature]
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13
[SID103516775]
IC50 Antioxidant activity assessed as inhibition of superoxide production by xanthine/xanthine oxidase method [AID293298, Type: Literature]
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14
[SID26719694]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) [AID2012, Type: confirmatory]Eukaryotic translation initiation factor 4H [Homo sapiens] [gi:45219878]
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15
[SID26719694]
IC50 uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) [AID2014, Type: confirmatory]polyadenylate-binding protein 1 [Homo sapiens] [gi:46367787]
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16
[SID26719694]
IC50 HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. [AID1209, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
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17
[SID103516775]
IC50 52.2Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
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18
[SID103516775]
IC50 52.2Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay [AID366285, Type: Literature]
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19
[SID103516775]
IC50 80Inhibition of CYP3A4 [AID380506, Type: Literature]
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20
[SID103516775]
IC50 87.7Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay [AID366284, Type: Literature]
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21
[SID103516775]
IC50 100Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay [AID366286, Type: Literature]
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22
[SID103516775]
IC50 100Cytotoxicity against human LCC-6 cells after 5 days by MTS assay [AID666853, Type: Literature]
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23
[SID103516775]
IC50 100Cytotoxicity against multidrug resistant human LCC-6 cells after 5 days by MTS assay [AID666854, Type: Literature]
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24
[SID103516775]
IC50 100Cytotoxicity against mouse L929 cells after 5 days by MTS assay [AID666855, Type: Literature]
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25
[SID103516775]
IC50 164Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay [AID379089, Type: Literature]
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26
[SID103516775]
IC50 294.46Antiglycation activity assessed as inhibition of BSA-derived advance glycated end product formation after 9 days by spectrophotometry [AID452625, Type: Literature]
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27
[SID103516775]
IC50 Inhibition of human HH/Gli1-mediated transcriptional activity in tetracycline-treated human HaCaT cells treated after 12 hrs of tetracycline addition by luciferase reporter gene assay [AID551196, Type: Literature]
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28
[SID49681540]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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29
[SID26719694]
IC50 HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate [AID1220, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
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30
[SID26719694]
IC50 uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. [AID1434, Type: confirmatory]core-binding factor subunit beta isoform 1 [Homo sapiens] [gi:13124881]
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31
[SID26719694]
IC50 uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. [AID1434, Type: confirmatory]runt-related transcription factor 1 isoform AML1c [Homo sapiens] [gi:19923198]
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32
[SID26719694]
IC50 Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) [AID1445, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:124512980]
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33
[SID26719694]
IC50 uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1 [AID1565, Type: confirmatory]phosphoethanolamine/phosphocholine phosphatase isoform 1 [Homo sapiens] [gi:219689097]
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34
[SID26719694]
IC50 Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) [AID1619, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:124809582]
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35
[SID26719694]
IC50 High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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36
[SID26719694]
IC50 HCS for Compounds that Down-Regulate Insulin Promoter Activity in MIN6 Cells [AID1628, Type: confirmatory]
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37
[SID26719694]
IC50 uHTS absorbance assay for the identification of compounds that inhibit VHR1. [AID1654, Type: confirmatory]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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38
[SID26719694]
IC50_Mean High Throughput Imaging Assay for Beta-Catenin [AID1665, Type: confirmatory]catenin beta-1 [Homo sapiens] [gi:4503131]
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39
[SID26719694]
IC50 uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay [AID1778, Type: confirmatory]kappa-type opioid receptor isoform 1 [Homo sapiens] [gi:39725940]
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40
[SID26719694]
IC50 uHTS identification of small molecule inhibitors of LYP via a fluorescence intensity assay [AID1779, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 22 isoform 1 [Homo sapiens] [gi:224586929]
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41
[SID26719694]
IC50 uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay. [AID1817, Type: confirmatory]plectin 1 [Homo sapiens] [gi:40849930]
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42
[SID26719694]
IC50 A small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID1863, Type: confirmatory]
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43
[SID26719694]
IC50 Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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44
[SID26719694]
IC50 Fluorescence for the identification of compounds that decrease p/CIP protein stability [AID1984, Type: confirmatory]nuclear receptor coactivator 3 [Mus musculus] [gi:118026946]
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45
[SID26719694]
IC50 uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
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46
[SID26719694]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO-conjugating enzyme UBC9 [Homo sapiens] [gi:4507785]
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47
[SID26719694]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]SUMO1 activating enzyme subunit 1 [Homo sapiens] [gi:17390638]
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48
[SID26719694]
IC50 uHTS HTRF assay for identification of inhibitors of SUMOylation [AID2006, Type: confirmatory]Ubiquitin-like modifier activating enzyme 2 [Homo sapiens] [gi:13111961]
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49
[SID26719694]
IC50 Image-Based HTS for Selective Antagonists of GPR35 [AID2058, Type: confirmatory]G-protein coupled receptor 35 isoform a [Homo sapiens] [gi:33695097]
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50
[SID26719694]
IC50 Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay [AID2073, Type: confirmatory]Mint1 [Rattus norvegicus] [gi:2625023]
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