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BioActivity Data for Compound Iodoquinol (CID 3728)

Filters: All Data » IC50      
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BioActivity Outcomes:
Active(18)
 
 
Inactive(43)
 
 
Inconclusive(5)
 
 
Unspecified(107)
 
 
Top Targets:
7tm 4(30)
 
 
 
p450(7)
 
 
prostaglandin..(2)
 
 
STKc ERK1 2 l..(2)
 
 
PTPc(2)
 
 
BioAssay Types:
Confirmatory(172)
 
 
 
 
 
Literature(1)
 
 
BioAssay Categories:
Biochemical(118)
 
 
 
 
Cell-based(90)
 
 
 
 
 
In vitro(117)
 
 
 
 
BioActivity Types:
IC50(173)
 
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 168    Data Row: 173   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170465640]
IC50 0.0036SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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2
[SID170465640]
IC50 0.0178DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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3
[SID170465640]
IC50 0.0213Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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4
[SID170465640]
IC50 0.0227RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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5
[SID170465640]
IC50 0.0387SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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6
[SID170465640]
IC50 0.04097HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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7
[SID103293005]
IC50 0.294DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) [AID625181, Type: confirmatory]Mitogen-activated protein kinase 1 [gi:119554]
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8
[SID103293005]
IC50 0.364DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) [AID625182, Type: confirmatory]Mitogen-activated protein kinase 14 [gi:2499600]
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9
[SID170465640]
IC50 0.7047HT-29 viability from Cell TiterGlo-IC50 [AID1117330, Type: confirmatory]
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10
[SID103293005]
IC50 0.906DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) [AID625173, Type: confirmatory]Angiotensin-converting enzyme [gi:2822103]
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11
[SID103293005]
IC50 0.933DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) [AID625196, Type: confirmatory]Adenosine receptor A3 [gi:1351831]
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12
[SID103293005]
IC50 1.571DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625185, Type: confirmatory]Tyrosine-protein kinase Fyn [gi:125370]
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13
[SID103293005]
IC50 1.889DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625184, Type: confirmatory]Epidermal growth factor receptor [gi:2811086]
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14
[SID170465640]
IC50 2.3935VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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15
[SID103293005]
IC50 2.461DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625187, Type: confirmatory]Tyrosine-protein kinase Lck [gi:125474]
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16
[SID103293005]
IC50 5.264DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) [AID625180, Type: confirmatory]Mitogen-activated protein kinase 3 [gi:232066]
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17
[SID103293005]
IC50 5.62341Inhibition of Sprague-Dawley rat liver COMT after 10 mins using 0.05 uCi [14CH3]-SAM as substrate [AID1149251, Type: Literature]Catechol O-methyltransferase [gi:116909]
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18
[SID103293005]
IC50 8.577DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625186, Type: confirmatory]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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19
[SID103293005]
IC50 DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) [AID625183, Type: confirmatory]Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [gi:1352673]
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20
[SID103293005]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) [AID625190, Type: confirmatory]
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