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Succinic Acid (CID 1110) - Compound BioActivity Data
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Filters: All Data » IC50      
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(6)
 
 
Top Targets:
P4Hc(3)
 
 
 
BioAssay Types:
Literature(8)
 
 
 
BioActivity Types:
IC50(8)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179217]
IC50 0.0013Anti-Herpes simplex virus type-1 activity in vero cells using plaque inhibition assay [AID216185, Type: Literature]
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2
[SID103179217]
IC50 3Inhibition of 2-oxoglutarate-dependent human recombinant HIF PHD2 preincubated for 1 hr [AID344926, Type: Literature]Egl nine homolog 1 [gi:32129514]
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3
[SID103179217]
IC50 85.3Inhibition of human PHD2 at 293K temperature by solvent relaxation technique [AID446353, Type: Literature]Egl nine homolog 1 [gi:32129514]
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4
[SID103179217]
IC50 85.3Destabilizing effect on human recombinant PHD2 (181-426) expressed in Escherichia coli BL21 (DE3) assessed as half life by limited trypsinolysis/MALDI-MS analysis in presence of ferrous ion [AID349748, Type: Literature]
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5
[SID103179217]
IC50 320Inhibition of 2-oxoglutarate-dependent human JMJD2E preincubated for 30 mins by FDH coupled assay [AID344918, Type: Literature]
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6
[SID103179217]
IC50 710Inhibition of 2-oxoglutarate-dependent human JMJD2E in presence of excess H3K9me3 peptide and 10 uM Fe2 by FDH coupled assay [AID344917, Type: Literature]
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7
[SID103179217]
IC50 10000Inhibition of PHD2 (unknown origin) [AID721521, Type: Literature]Egl nine homolog 1 [gi:32129514]
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8
[SID103179217]
IC50 10000Inhibition of 2-oxoglutarate-dependent human JMJD2E in presence of excess 2-oxoglutarate and 10 uM Fe2 by FDH coupled assay [AID344916, Type: Literature]
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