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2-Anilino-1,4-naphthoquinone (CID 81124) - Compound BioActivity Data
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Filters: All Data » EC50      
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BioActivity Outcomes:
Active(4)
 
 
Inactive(15)
 
 
Top Targets:
Bcl-2 like(6)
 
 
NACHT(2)
 
 
7TM GPCR Srx(1)
 
 
GST C Mu(1)
 
 
HSF(1)
 
 
BioAssay Types:
Confirmatory(18)
 
 
 
Literature(1)
 
 
BioActivity Types:
EC50(19)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 18    Data Row: 19   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103284973]
EC50 0.239Inhibitory activity on acetylcholine-induced vasorelaxation of phenylephrine-precontracted rat aorta with intact endothelium [AID175494, Type: Literature]
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2
[SID24824101]
EC50_uM 1.26Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) [AID435004, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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3
[SID24824101]
EC50 1.348Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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4
[SID24824101]
EC50 1.348Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]transcription factor p65 isoform 1 [Homo sapiens] [gi:223468676]
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5
[SID24824101]
EC50_MICROM Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1. [AID1320, Type: confirmatory]bcl-2-related protein A1 isoform 1 [Homo sapiens] [gi:4757840]
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6
[SID24824101]
EC50_MICROM Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1322, Type: confirmatory]bcl-xL [Homo sapiens] [gi:510901]
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7
[SID24824101]
EC50_MICROM Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) [AID1324, Type: confirmatory]glutathione S-transferase, partial [Homo sapiens] [gi:31933]
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8
[SID24824101]
EC50_MICROM Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. [AID1327, Type: confirmatory]Bcl-2-like protein 10 [gi:23396469]
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9
[SID24824101]
EC50_MICROM Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 [AID1328, Type: confirmatory]Apoptosis regulator Bcl-2 [gi:231632]
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10
[SID24824101]
EC50_MICROM Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1. [AID1329, Type: confirmatory]Mcl-1 [Homo sapiens] [gi:7582271]
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11
[SID24824101]
EC50_MICROM Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. [AID1330, Type: confirmatory]Bcl-w [Homo sapiens] [gi:1572493]
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12
[SID24824101]
EC50 Screen for small molecule probes relevant to Friedreich's ataxia, Single Dose and Dose Response [AID1465, Type: confirmatory]
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13
[SID24824101]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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14
[SID24824101]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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15
[SID24824101]
EC50 HCS for Compounds that Up-Regulate Insulin Promoter Activity in MIN6 Cells [AID1625, Type: confirmatory]
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16
[SID24824101]
EC50 uHTS identification of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay [AID1777, Type: confirmatory]kappa-type opioid receptor isoform 1 [Homo sapiens] [gi:39725940]
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17
[SID24824101]
EC50 Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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18
[SID24824101]
EC50 uHTS identification of compounds activating TNAP in the absence of phosphate acceptor performed in luminescent assay [AID1001, Type: confirmatory]alkaline phosphatase, tissue-nonspecific isozyme isoform 1 precursor [Homo sapiens] [gi:116734717]
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19
[SID24824101]
EC50 High Throughput Screen for Inhibitors of ER Stress-induced Cell Death in a 384 well format. [AID1222, Type: confirmatory]
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