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Dopamine (CID 681) - Compound BioActivity Data
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Filters: All Data » EC50      
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BioActivity Outcomes:
Active(59)
 
 
Top Targets:
7tm 4(33)
 
 
FAM101(2)
 
 
Herpes DNAp a..(1)
 
 
BioAssay Types:
Literature(59)
 
 
BioActivity Types:
EC50(59)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 59    Data Row: 59   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103167911]
EC50 0.0011Agonist activity at rat D2 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274445, Type: Literature]D(2) dopamine receptor [gi:47117674]
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2
[SID103167911]
EC50 0.0011In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay [AID61225, Type: Literature]
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3
[SID103167911]
EC50 0.0018Agonist activity at dopamine D3 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay [AID750640, Type: Literature]D(3) dopamine receptor [gi:1169206]
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4
[SID103167911]
EC50 0.0022Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274437, Type: Literature]D(4) dopamine receptor [gi:1345939]
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5
[SID103167911]
EC50 0.0022In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assay [AID65928, Type: Literature]
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6
[SID103167911]
EC50 0.0024In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assay [AID63828, Type: Literature]
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7
[SID103167911]
EC50 0.0024Agonist activity at rat D4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274442, Type: Literature]D(4) dopamine receptor [gi:6226851]
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8
[SID103167911]
EC50 0.0027In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assay [AID63703, Type: Literature]
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9
[SID103167911]
EC50 0.0027Agonist activity at ferret D4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR [AID274441, Type: Literature]
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10
[SID103167911]
EC50 0.00476Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay [AID461563, Type: Literature]D(3) dopamine receptor [gi:1169206]
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11
[SID103167911]
EC50 0.00476Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID513742, Type: Literature]D(3) dopamine receptor [gi:1169206]
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12
[SID103167911]
EC50 0.005Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production [AID272396, Type: Literature]D(2) dopamine receptor [gi:47117674]
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13
[SID103167911]
EC50 0.0058Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assay [AID712282, Type: Literature]D(3) dopamine receptor [gi:1169206]
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14
[SID103167911]
EC50 0.0061Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine incorporation assay [AID709655, Type: Literature]D(3) dopamine receptor [gi:1169206]
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15
[SID103167911]
EC50 0.0067Agonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay [AID750644, Type: Literature]D(2) dopamine receptor [gi:118206]
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16
[SID103167911]
EC50 0.00764Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation counting analysis [AID750042, Type: Literature]D(3) dopamine receptor [gi:1169206]
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17
[SID103167911]
EC50 0.008In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay [AID61221, Type: Literature]
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18
[SID103167911]
EC50 0.008Agonist activity at ferret D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR [AID274444, Type: Literature]
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19
[SID103167911]
EC50 0.00853Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS binding [AID384700, Type: Literature]D(3) dopamine receptor [gi:1169206]
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20
[SID103167911]
EC50 0.00853Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTP-gamma-S binding [AID312287, Type: Literature]D(3) dopamine receptor [gi:1169206]
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