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Aspirin (CID 2244) - Compound BioActivity Data
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Filters: All Data » EC50      
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BioActivity Outcomes:
Inactive(9)
 
 
Unspecified(1)
 
 
Top Targets:
Rac1 like(2)
 
 
Ras like GTPa..(2)
 
 
Rab2(1)
 
 
Rab7(1)
 
 
BioAssay Types:
Confirmatory(9)
 
 
Literature(1)
 
 
BioActivity Types:
EC50(10)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164874]
EC50 1000Apoptosis induction in human HT29 cells after 24 hrs [AID286677, Type: Literature]
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2
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID2021, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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3
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID2022, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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4
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID2036, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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5
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID2038, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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6
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant [AID2039, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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7
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype [AID2040, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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8
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant [AID2043, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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9
[SID81067407]
EC50_MICROM 30Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID2046, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
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10
[SID47193676]
EC50 Screen for small molecule probes relevant to Friedreich's ataxia, Single Dose and Dose Response [AID1465, Type: confirmatory]
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