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BioActivity Data for Target Serine/threonine-protein kinase Sgk1 [gi:90185131]

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BioActivity Outcomes:
Active(42)
 
 
BioAssay Types:
Literature(42)
 
 
BioAssay Categories:
Biochemical(42)
 
 
Cell-based(17)
 
 
BioActivity Types:
IC50(34)
 
 
Substance Types:
Chemical(42)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 42   Total Pages: 3   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID194145292]
[CID71506845]
IC50 0.001Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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2
[SID194152132]
[CID71537835]
IC50 0.002Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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3
[SID194145290]
[CID71537263]
IC50 0.002Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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4
[SID194186598]
[CID71537836]
IC50 0.002Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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5
[SID194145291]
[CID71537540]
IC50 0.002Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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6
[SID194159099]
[CID71537834]
IC50 0.003Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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7
[SID194179797]
[CID71536970]
IC50 0.003Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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8
[SID194159098]
[CID71537544]
IC50 0.004Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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9
[SID194179798]
[CID71537261]
IC50 0.005Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluorescence assay [AID1056407, Type: Literature]
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10
[SID242612930]
[CID72698602]
IC50 0.005Inhibition of SGK1 (unknown origin) [AID1119796, Type: Literature]
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11
[SID174493954]
[CID54764565]
IC50 0.201Inhibition of wild type human SGK1 by high throughput ATP-[33P] radiolabeled assay [AID775405, Type: Literature]
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12
[SID103542958]
[CID11248502]
IC50 0.29Inhibition of human SGK [AID301981, Type: Literature]
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13
[SID103686588]
[CID45270042]
IC50 0.58Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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14
[SID103691849]
[CID25022668]
IC50 0.58Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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15
[SID194179798]
[CID71537261]
IC50 0.63Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hrs by fluorescence assay [AID1056406, Type: Literature]
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16
[SID194145292]
[CID71506845]
IC50 0.69Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hrs by fluorescence assay [AID1056406, Type: Literature]
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17
[SID103690054]
[CID45271705]
IC50 0.71Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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18
[SID103683074]
[CID45268304]
IC50 0.87Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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19
[SID103690046]
[CID11952989]
IC50 0.88Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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20
[SID103686574]
[CID11544170]
IC50 1.3Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiological transepithelial experiment [AID427884, Type: Literature]
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