Bookmark and Share
metabotropic glutamate receptor 5 precursor [.. [gi:8393490] - Target BioActivity Data
Also known as: metabotropic glutamate receptor 5 precursor [Rattus norvegicus].
Filters: All Data » Active      
Filter selected
BioActivity Outcomes:
Probe(22)
 
 
Active(63)
 
 
BioAssay Types:
Confirmatory(82)
 
 
 
BioActivity Types:
EC50(60)
 
 
 
IC50(2)
 
 
Substance Types:
Chemical(85)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 85   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID126920341]
[CID53384864]
Average_IC50_uM 0.00483533mGluR5_3H_methoxyPEPy_Binding [AID588710, Type: confirmatory]
View
2
[SID160963303]
[CID70789094]
Ki_uM 0.01Discovery of Novel Silent Allosteric Modulators (SAM) of the Metabotropic Glutamate Receptor 5: 3pt binding Assay [AID652191, Type: confirmatory]
View
3
[SID160963303]
[CID70789094]
Average_Ki_uM 0.0182Discovery of Novel Silent Allosteric Modulators (SAM) of the Metabotropic Glutamate Receptor 5: full Ki determination [AID652196, Type: confirmatory]
View
4
[SID144241536]
[CID4384110]
Average_EC50_uM 0.049Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
5
[SID144241535]
[CID1364364]
Average_EC50_uM 0.051Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
6
[SID125305189]
[CID53382545]
Average_IC50_uM 0.0575mGluR5_3H_methoxyPEPy_Binding [AID588710, Type: confirmatory]
View
7
[SID144241562]
[CID60210908]
Average_EC50_uM 0.085Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
8
[SID160963303]
[CID70789094]
Average_EC50_MICROMOLAR 0.1363Discovery of Novel Silent Allosteric Modulators (SAM) of the Metabotropic Glutamate Receptor 5: Fold-shift Assay [AID652198, Type: confirmatory]
View
9
[SID144241527]
[CID60210882]
Average_EC50_uM 0.298Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
10
[SID144241541]
[CID60210914]
Average_EC50_uM 0.427Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
11
[SID144241540]
[CID60210915]
Average_EC50_uM 0.944Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
12
[SID144241561]
[CID60210917]
Average_EC50_uM 1.393Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
13
[SID144241537]
[CID60210899]
Average_EC50_uM 1.688Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
14
[SID144241539]
[CID60210911]
Average_EC50_uM 1.744Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
15
[SID144241564]
[CID1318633]
Average_EC50_uM 2.411Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
16
[SID144241560]
[CID60210894]
Average_EC50_uM 2.456Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
17
[SID144241551]
[CID60210906]
Average_EC50_uM 3.619Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
18
[SID144241538]
[CID60210913]
Average_EC50_uM 4.395Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
19
[SID144241553]
[CID60210918]
Average_EC50_uM 4.435Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View
20
[SID144241542]
[CID3433401]
Average_EC50_uM 4.53Identification of a glycine sulfonamide based non-MPEP site positive allosteric potentiator (PAM) of mGlu5 (calcium_assay) [AID651835, Type: confirmatory]
View