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Induced myeloid leukemia cell differentiation.. [gi:81882221] - Target BioActivity Data
Also known as: Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Bcl-2-related protein EAT/mcl1.
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BioActivity Outcomes:
Active(10)
 
 
BioAssay Types:
Literature(10)
 
 
BioActivity Types:
IC50(5)
 
 
Ki(4)
 
 
Kd(1)
 
 
Substance Types:
Chemical(10)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 10   Total Pages: 1   
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID136945113]
[CID57403327]
Ki 1.5Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by fluorescence polarization competition assay [AID628491, Type: Literature]
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2
[SID136925703]
[CID57392877]
Ki 2Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by fluorescence polarization competition assay [AID628491, Type: Literature]
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3
[SID136925704]
[CID57392878]
Ki 2Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by fluorescence polarization competition assay [AID628491, Type: Literature]
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4
[SID136932147]
[CID57396359]
Ki 2Displacement of BODIPY-Bak conjugated peptide from GST-tagged mouse wild type MCL1 expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by fluorescence polarization competition assay [AID628491, Type: Literature]
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5
[SID103750863]
[CID6535736]
IC50 6.4Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay [AID478112, Type: Literature]
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6
[SID103750988]
[CID6520864]
IC50 8.6Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay [AID478112, Type: Literature]
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7
[SID103751232]
[CID6512895]
IC50 18.6Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay [AID478112, Type: Literature]
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8
[SID103751305]
[CID46887149]
IC50 19.2Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay [AID478112, Type: Literature]
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9
[SID103623515]
[CID44578246]
Kd 25Binding affinity to mouse Mcl-1 expressed in Escherichia coli BL21 cells [AID341219, Type: Literature]
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10
[SID103751306]
[CID46887150]
IC50 34.4Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay [AID478112, Type: Literature]
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