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Telomerase reverse transcriptase; HEST2; Telo.. [gi:6226780] - Target BioActivity Data
Also known as: Telomerase reverse transcriptase; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2.
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BioActivity Outcomes:
Active(391)
 
 
BioAssay Types:
Literature(391)
 
 
BioActivity Types:
IC50(281)
 
 
EC50(73)
 
 
Substance Types:
Chemical(391)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 57    Data Row: 391   Total Pages: 8   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103635202]
[CID443590]
IC50 0.00064Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assay [AID329708, Type: Literature]
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2
[SID103635202]
[CID443590]
IC50 0.0007Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assay [AID329709, Type: Literature]
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3
[SID103635202]
[CID443590]
IC50 0.0007Inhibition of human Telomerase activity in cell free system by TRAP assay [AID587556, Type: Literature]
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4
[SID103564654]
[CID44449504]
IC50 0.0015Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assay [AID329708, Type: Literature]
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5
[SID103564654]
[CID44449504]
IC50 0.0022Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assay [AID329709, Type: Literature]
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6
[SID103743676]
[CID10121143]
IC50 0.018Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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7
[SID103377944]
[CID10119878]
IC50 0.018Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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8
[SID103377677]
[CID10188027]
IC50 0.02Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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9
[SID103514198]
[CID14573901]
IC50 0.03Inhibition of telomerase in JR8 cell extract by TRAP assay [AID283979, Type: Literature]
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10
[SID103545596]
[CID11570708]
EC50 0.03Inhibition of human telomerase by TRAP assay [AID306427, Type: Literature]
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11
[SID103377898]
[CID10121310]
IC50 0.04Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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12
[SID103378356]
[CID9808666]
IC50 0.045Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assay [AID329708, Type: Literature]
View
13
[SID103564608]
[CID11430774]
IC50 0.045Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assay [AID329712, Type: Literature]
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14
[SID103378433]
[CID10164700]
IC50 0.05Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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15
[SID103378643]
[CID10303830]
IC50 0.05Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
16
[SID103564608]
[CID11430774]
IC50 0.052Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assay [AID329708, Type: Literature]
View
17
[SID103635202]
[CID443590]
IC50 0.058Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assay [AID329712, Type: Literature]
View
18
[SID103514197]
[CID44421795]
IC50 0.06Inhibition of telomerase in JR8 cell extract by TRAP assay [AID283979, Type: Literature]
View
19
[SID103377897]
[CID10120540]
IC50 0.06Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
20
[SID103378189]
[CID10166451]
IC50 0.06Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
21
[SID163331385]
[CID11979833]
IC50 0.06Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by telomeric repeat amplification protocol [AID704076, Type: Literature]
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22
[SID103564608]
[CID11430774]
IC50 0.063Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assay [AID329709, Type: Literature]
View
23
[SID103564654]
[CID44449504]
IC50 0.063Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assay [AID329712, Type: Literature]
View
24
[SID103378356]
[CID9808666]
IC50 0.065Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assay [AID329709, Type: Literature]
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25
[SID103477068]
[CID10212113]
EC50 0.067Inhibition of telomerase activity from human A2780 cells [AID257826, Type: Literature]
View
26
[SID103377848]
[CID10303368]
IC50 0.07Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
27
[SID103377994]
[CID9915945]
IC50 0.074Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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28
[SID103377845]
[CID10231493]
IC50 0.08Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
29
[SID103377988]
[CID10166452]
IC50 0.08Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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30
[SID103448648]
[CID10056382]
EC50 0.08Effective concentration against telomerase by TRAP [AID240076, Type: Literature]
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31
[SID103448648]
[CID10056382]
IC50 0.08Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
32
[SID103378356]
[CID9808666]
IC50 0.09Inhibition of human telomerase in A549 cells by TRAP assay [AID437317, Type: Literature]
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33
[SID103453342]
[CID44395808]
EC50 0.09Concentration required to inhibit 50% of telomerase activity [AID240050, Type: Literature]
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34
[SID103377947]
[CID10303003]
IC50 0.09Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
35
[SID103196266]
[CID9927531]
IC50 0.093Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assay [AID704074, Type: Literature]
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36
[SID103448647]
[CID10350345]
EC50 0.098Effective concentration against telomerase by TRAP [AID240076, Type: Literature]
View
37
[SID103448647]
[CID10350345]
IC50 0.098Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
38
[SID103477238]
[CID11700099]
EC50 0.099Inhibition of telomerase activity from human A2780 cells [AID257826, Type: Literature]
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39
[SID103378356]
[CID9808666]
IC50 0.1Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
40
[SID103377899]
[CID10304003]
IC50 0.1Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
41
[SID103377995]
[CID10167766]
IC50 0.1Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
42
[SID103377846]
[CID9830102]
IC50 0.1Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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43
[SID103377757]
[CID10120541]
IC50 0.11Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
View
44
[SID103378356]
[CID9808666]
EC50 0.113Effective concentration against telomerase by TRAP [AID240076, Type: Literature]
View
45
[SID103378356]
[CID9808666]
EC50 0.113Inhibition of telomerase activity from human A2780 cells [AID257826, Type: Literature]
View
46
[SID103477069]
[CID11534942]
EC50 0.117Inhibition of telomerase activity from human A2780 cells [AID257826, Type: Literature]
View
47
[SID103378356]
[CID9808666]
EC50 0.12Inhibition of human telomerase by TRAP assay [AID306427, Type: Literature]
View
48
[SID103512535]
[CID9966473]
IC50 0.13Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assay [AID281989, Type: Literature]
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49
[SID103377946]
[CID10186874]
IC50 0.14Inhibition of telomerase in human A2780 cells by TRAP assay [AID471962, Type: Literature]
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50
[SID103477043]
[CID11498709]
EC50 0.146Inhibition of telomerase activity from human A2780 cells [AID257826, Type: Literature]
View