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Prostaglandin G/H synthase 1; Cyclooxygenase-.. [gi:548481] - Target BioActivity Data
Also known as: Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1.
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BioActivity Outcomes:
Active(793)
 
 
BioAssay Types:
Literature(750)
 
 
Confirmatory(43)
 
 
BioActivity Types:
IC50(771)
 
 
Kd(5)
 
 
Ki(5)
 
 
Substance Types:
Chemical(793)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 143    Data Row: 793   Total Pages: 40   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103168269]
[CID73324]
IC50 0.001Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirin [AID162144, Type: Literature]
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2
[SID103168276]
[CID68215]
IC50 0.001Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirin [AID162144, Type: Literature]
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3
[SID103168306]
[CID94776]
IC50 0.001Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirin [AID162144, Type: Literature]
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4
[SID103635887]
[CID11649268]
IC50 0.001Inhibition of ovine COX1 [AID377009, Type: Literature]
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5
[SID103635900]
[CID11519421]
IC50 0.001Inhibition of ovine COX1 [AID377009, Type: Literature]
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6
[SID103635901]
[CID44583799]
IC50 0.001Inhibition of ovine COX1 [AID377009, Type: Literature]
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7
[SID103181002]
[CID2662]
IC50 0.0037Inhibition of COX1 [AID270013, Type: Literature]
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8
[SID103497297]
[CID16007065]
IC50 0.0038Inhibition of COX1 [AID270013, Type: Literature]
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9
[SID103163840]
[CID3715]
IC50 0.004Inhibition of ovine COX1 [AID271286, Type: Literature]
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10
[SID104244877]
[CID46934868]
IC50 0.004Inhibition of sheep COX1 by enzyme immunoassay [AID502274, Type: Literature]
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11
[SID103497298]
[CID16007066]
IC50 0.0041Inhibition of COX1 [AID270013, Type: Literature]
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12
[SID103163840]
[CID3715]
IC50 0.006Inhibition of ovine COX1 after 5 mins [AID492859, Type: Literature]
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13
[SID103163840]
[CID3715]
IC50 0.006Inhibition of ovine COX-1 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid by HPLC analysis [AID614601, Type: Literature]
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14
[SID103163840]
[CID3715]
IC50 0.0067Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 1 min prior to substrate addition measured for 25 secs by TMPD-based chromogenic assay [AID695143, Type: Literature]
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15
[SID103199497]
[CID4306515]
IC50 0.0085Inhibition of ovine COX1 by fluorescence assay [AID657242, Type: Literature]
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16
[SID103325387]
[CID22810]
IC50 0.01In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheep [AID162021, Type: Literature]
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17
[SID123101585]
[CID9945282]
IC50 0.01Inhibition of ovine COX1 by colorimetric assay [AID701950, Type: Literature]
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18
[SID103178857]
[CID3394]
IC50 0.011In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheep [AID162021, Type: Literature]
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19
[SID103178857]
[CID3394]
IC50 0.012Reversible competitive inhibition of prostaglandin G/H synthase 1 [AID162150, Type: Literature]
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20
[SID103163840]
[CID3715]
IC50 0.0122IC50 value against ovine Prostaglandin G/H synthase 1 [AID162016, Type: Literature]
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