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Microtubule-associated protein tau; Neurofibr.. [gi:334302961] - Target BioActivity Data
Also known as: Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau.
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BioActivity Outcomes:
Active(62)
 
 
BioAssay Types:
Literature(56)
 
 
BioActivity Types:
Ki(7)
 
 
IC50(7)
 
 
Kd(1)
 
 
Substance Types:
Chemical(62)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 62   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID163339664]
[CID71463212]
IC50 0.00141Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
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2
[SID103169156]
[CID3883]
Ki 0.0025Binding affinity to heparin induced human Tau 441 at 50 pM to 500 nM after 30 mins [AID712328, Type: other]
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3
[SID163329269]
[CID71457851]
IC50 0.0051Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
View
4
[SID160685844]
[CID70688786]
Ki 0.017Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assay [AID677224, Type: Literature]
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5
[SID160668297]
[CID56950117]
Kd 0.0448Binding affinity to recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay [AID663428, Type: other]
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6
[SID160693422]
[CID7083]
Ki 0.069Inhibition of recombinant tau (unknown origin) aggregation [AID729973, Type: Literature]
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7
[SID160707358]
[CID70697093]
Ki 0.112Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assay [AID677224, Type: Literature]
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8
[SID163332133]
[CID16049314]
IC50 0.246Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
View
9
[SID160689667]
[CID56950118]
IC50 0.256Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay [AID663425, Type: other]
View
10
[SID160669871]
[CID57176479]
Ki 0.599Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assay [AID677224, Type: Literature]
View
11
[SID160680540]
[CID70686684]
Ki 1.428Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assay [AID677224, Type: Literature]
View
12
[SID103486872]
[CID24858429]
IC50 1.635Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
View
13
[SID103303707]
[CID10171487]
IC50 3.255Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
View
14
[SID134461196]
[CID56681824]
Displacement of Thioflavin S from recombinant human PHF-tau expressed in Escherichia coli by fluorescence assay [AID614071, Type: Literature]
View
15
[SID160668297]
[CID56950117]
Binding affinity to tau protein in human alzheimer's disease patient brain white matter at 92.5 kBq after 2 hrs by immunohistological staining [AID663432, Type: other]
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16
[SID160700491]
[CID70694381]
IC50 Displacement of Thioflavin S from recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay [AID663425, Type: other]
View
17
[SID163329269]
[CID71457851]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View
18
[SID163339664]
[CID71463212]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View
19
[SID163339665]
[CID71463214]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View
20
[SID163332134]
[CID50936651]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
21
[SID163332134]
[CID50936651]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
22
[SID163332135]
[CID71459256]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
23
[SID163332135]
[CID71459256]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
24
[SID163332136]
[CID71459257]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
25
[SID163332136]
[CID71459257]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
26
[SID163332137]
[CID71459258]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
27
[SID163332137]
[CID71459258]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
28
[SID163332287]
[CID71459376]
Ki Binding affinity to heparin induced human Tau 441 at 50 pM to 500 nM after 30 mins [AID712328, Type: other]
View
29
[SID163335580]
[CID56933066]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
30
[SID163335580]
[CID56933066]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
31
[SID163335642]
[CID71461085]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
32
[SID163335642]
[CID71461085]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
33
[SID163335643]
[CID71461086]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
34
[SID163335643]
[CID71461086]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
35
[SID163338980]
[CID71462763]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
36
[SID163338980]
[CID71462763]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
37
[SID163338981]
[CID71462764]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
38
[SID163338981]
[CID71462764]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
39
[SID163314826]
[CID71450236]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
40
[SID163314826]
[CID71450236]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
41
[SID163314827]
[CID42643531]
Binding affinity to tau aggregate in Alzheimer patient bowmans gland of olfactory epithelium [AID706431, Type: Literature]
View
42
[SID163314827]
[CID42643531]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
43
[SID163314827]
[CID42643531]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
44
[SID163318350]
[CID71452100]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
45
[SID163318350]
[CID71452100]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
46
[SID163318997]
[CID15509023]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View
47
[SID163321838]
[CID71453931]
Binding affinity to extracellular tau plaques in Alzheimer patient brain by fluorescence microscopic analysis [AID706441, Type: Literature]
View
48
[SID163321838]
[CID71453931]
Binding affinity to intracellular fibrillar tau in Alzheimer patient brain by fluorescence microscopic analysis [AID706442, Type: Literature]
View
49
[SID163322442]
[CID71454302]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View
50
[SID163322443]
[CID71454303]
Binding affinity to Tau aggregates in Alzheimer patient hippocampus by fluorescence microscopy [AID718588, Type: Literature]
View