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BioActivity Data for Target Microtubule-associated protein tau [gi:334302961]

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BioActivity Outcomes:
Active(100)
 
 
BioAssay Types:
Literature(100)
 
 
BioActivity Types:
IC50(28)
 
 
Ki(7)
 
 
Kd(4)
 
 
Substance Types:
Chemical(100)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 24    Data Row: 100   Total Pages: 5   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID242645766]
[CID73297137]
IC50 0.001Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
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2
[SID163339664]
[CID71463212]
IC50 0.00141Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
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3
[SID242645760]
[CID73296378]
IC50 0.002Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
4
[SID242645761]
[CID73296809]
IC50 0.002Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
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5
[SID242645762]
[CID90644922]
IC50 0.002Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
6
[SID103169156]
[CID3883]
Ki 0.0025Binding affinity to heparin induced human Tau 441 at 50 pM to 500 nM after 30 mins [AID712328, Type: Literature]
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7
[SID242645767]
[CID73297139]
IC50 0.003Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
8
[SID242645759]
[CID90040128]
IC50 0.005Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
9
[SID242645763]
[CID73296810]
IC50 0.005Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
10
[SID163329269]
[CID71457851]
IC50 0.0051Displacement of thiazine red R from human Tau aggregate expressed in Escherichia coli after 30 mins by fluorimetric analysis [AID718586, Type: Literature]
View
11
[SID242645765]
[CID90644924]
IC50 0.008Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
12
[SID242645768]
[CID73294880]
IC50 0.013Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
13
[SID160685844]
[CID70688786]
Ki 0.017Binding affinity to human Tau aggregates after 30 mins by Thioflavin-S-based fluorescence assay [AID677224, Type: Literature]
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14
[SID160668297]
[CID56950117]
Kd 0.0448Binding affinity to recombinant human tau expressed in Escherichia coli after 30 mins by fluorescence assay [AID663428, Type: Literature]
View
15
[SID160693422]
[CID7083]
Ki 0.069Inhibition of recombinant tau (unknown origin) aggregation [AID729973, Type: Literature]
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16
[SID160693422]
[CID7083]
IC50 0.069Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysis [AID748711, Type: Literature]
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17
[SID103709786]
[CID65043]
IC50 0.069Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysis [AID748711, Type: Literature]
View
18
[SID103745049]
[CID13735]
IC50 0.069Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysis [AID748711, Type: Literature]
View
19
[SID242645764]
[CID90644923]
IC50 0.079Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay [AID1156051, Type: Literature]
View
20
[SID174505162]
[CID54581735]
IC50 0.08Inhibition of tau protein aggregation (unknown origin) [AID748699, Type: Literature]
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