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Lysosomal alpha-glucosidase; Acid maltase; Ag.. [gi:317373572] - Target BioActivity Data
Also known as: Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase.
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BioActivity Outcomes:
Active(29)
 
 
BioAssay Types:
Literature(29)
 
 
BioActivity Types:
IC50(15)
 
 
Substance Types:
Chemical(29)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 29   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID103278185]
[CID29435]
IC50 0.06Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]
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2
[SID103624146]
[CID444020]
IC50 0.07Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]
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3
[SID103277564]
[CID51634]
IC50 0.1Inhibition of human lysosomal alpha glucosidase [AID437995, Type: Literature]
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4
[SID103617394]
[CID159496]
IC50 0.1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]
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5
[SID103582154]
[CID441314]
IC50 0.35Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
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6
[SID103698575]
[CID9822159]
IC50 0.4Inhibition of human lysosomal alpha glucosidase [AID437995, Type: Literature]
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7
[SID103582154]
[CID441314]
IC50 1Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]
View
8
[SID103278185]
[CID29435]
IC50 1Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
View
9
[SID103617394]
[CID159496]
IC50 1Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
View
10
[SID103278185]
[CID29435]
IC50 1.5Inhibition of human lysosomal alpha glucosidase [AID437995, Type: Literature]
View
11
[SID103585278]
[CID444254]
IC50 5Inhibition of maltase in human Caco-2 cell model system after 2 hrs [AID342811, Type: Literature]
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12
[SID103624146]
[CID444020]
IC50 5.6Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
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13
[SID103624144]
[CID457676]
IC50 18Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
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14
[SID164142066]
[CID71570063]
IC50 21.05Inhibition of pure alpha-glucosidase (unknown origin) assessed as para-nitrophenol release at 420 nm OD [AID724304, Type: Literature]
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15
[SID103585278]
[CID444254]
IC50 42Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]
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16
[SID103582154]
[CID441314]
Inhibition of alpha-glucosidase in human HepG2 cells assessed as increase in expression of immature high mannose type N-linked oligosachcharides at 500 uM after 48 hrs by MALDI-TOF MS analysis relative to untreated control [AID710949, Type: Literature]
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17
[SID103582154]
[CID441314]
Lysosomal alpha-glucosidase inhibitor [AID742963, Type: Literature]
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18
[SID163312420]
[CID20969430]
Increase in GAA activity in human wild type skin fibroblasts incubated for 5 days by fluorescence assay relative to vehicle-treated control [AID705407, Type: Literature]
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19
[SID163312420]
[CID20969430]
Increase in GAA activity in human F2845 cells incubated for 5 days by fluorescence assay relative to vehicle-treated control [AID705411, Type: Literature]
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20
[SID163312420]
[CID20969430]
Increase in GAA activity in human F2845 cells incubated for 5 days followed by 18 to 40 hrs wash out by fluorescence assay relative to vehicle-treated control [AID705416, Type: Literature]
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