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metallo-beta-lactamase IMP-1 [Pseudomonas aer.. [gi:27368096] - Target BioActivity Data
Also known as: metallo-beta-lactamase IMP-1 [Pseudomonas aeruginosa].
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BioActivity Outcomes:
Probe(3)
 
 
Active(1473)
 
 
BioAssay Types:
Screening(1443)
 
 
Confirmatory(27)
 
 
 
BioActivity Types:
IC50(26)
 
 
 
Ki(1)
 
 
Substance Types:
Chemical(1476)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 1476   Total Pages: 30   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID125264855]
[CID53362017]
MIC [4 fold reduction] 0.781Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
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2
[SID134220672]
[CID53362017]
Ki 0.93Late stage assay provider results from the probe development efforts to identify nonselective inhibitors of VIM-2 metallo-beta-lactamase: Absorbance-based biochemical assays to determine the ability of probe candidates and selected analogs to inhibit IMP-1 [AID624084, Type: confirmatory]
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3
[SID125264855]
[CID53362017]
IC50 3.018Late stage assay provider results from the probe development efforts to identify nonselective inhibitors of VIM-2 metallo-beta-lactamase: Absorbance-based biochemical assays to determine the ability of probe candidates and selected analogs to inhibit IMP-1 [AID624085, Type: confirmatory]
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4
[SID49679995]
[CID2818392]
IC50 0.39877Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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5
[SID131269027]
[CID54579797]
MIC [4 fold reduction] 0.781Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
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6
[SID126723253]
[CID53495082]
MIC [4 fold reduction] 0.781Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
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7
[SID26659839]
[CID776411]
IC50 1.024Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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8
[SID92192482]
[CID45105306]
IC50 1.327Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
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9
[SID92192480]
[CID10448266]
IC50 1.507Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
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10
[SID125311278]
[CID53384679]
MIC [4 fold reduction] 1.563Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
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11
[SID848038]
[CID650462]
IC50 1.622Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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12
[SID92192478]
[CID45105304]
IC50 1.806Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
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13
[SID7971429]
[CID1789058]
IC50 2.115Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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14
[SID92192479]
[CID45105307]
IC50 2.33Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
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15
[SID22409753]
[CID3517787]
IC50 2.51Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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16
[SID22405113]
[CID3614365]
IC50 2.777Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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17
[SID124767346]
[CID53308605]
MIC [4 fold reduction] 3.125Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
View
18
[SID126723255]
[CID53495083]
MIC [4 fold reduction] 3.125Late stage assay provider results from the probe development efforts to identify inhibitors of VIM-2 metallo-beta-lactamase (nonselective):IMP-1-transformed E. coli growth inhibition in the presence of imipenem (synergy) [AID624097, Type: other]
View
19
[SID7977150]
[CID94381]
IC50 3.241Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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20
[SID22405114]
[CID5199378]
IC50 3.319Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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21
[SID24826438]
[CID4406525]
IC50 3.498Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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22
[SID92192481]
[CID45105308]
IC50 3.744Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
View
23
[SID49665326]
[CID3109741]
IC50 3.924Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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24
[SID24826744]
[CID3596034]
IC50 4.225Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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25
[SID22405109]
[CID4076033]
IC50 5.072Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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26
[SID862610]
[CID663844]
IC50 5.385Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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27
[SID17504691]
[CID2931982]
IC50 5.62Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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28
[SID24830438]
[CID4208272]
IC50 6.862Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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29
[SID4250548]
[CID712714]
IC50 8.007Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
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30
[SID49667306]
[CID3801816]
IC50 8.62Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
View
31
[SID92192477]
[CID1730]
IC50 8.696Late stage results from the probe development effort to identify common IMP-1 and VIM-2 inhibitors: Epi-absorbance-based biochemical dose response assay for inhibitors of IMP-1metallo-beta-lactamase [AID2768, Type: confirmatory]
View
32
[SID49666851]
[CID9642859]
IC50 8.927Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
View
33
[SID22402458]
[CID839988]
IC50 9.304Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase [AID2756, Type: confirmatory]
View
34
[SID22403612]
[CID4326780]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
35
[SID22403750]
[CID2339924]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
36
[SID22403785]
[CID1318356]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
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37
[SID22404228]
[CID15944971]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
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38
[SID22404237]
[CID1016460]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
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39
[SID22404912]
[CID6724]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
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40
[SID22404916]
[CID12273833]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
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41
[SID22404974]
[CID15945026]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
42
[SID22405109]
[CID4076033]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
43
[SID22405109]
[CID4076033]
Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. [AID2189, Type: screening]
View
44
[SID22405113]
[CID3614365]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
45
[SID22405113]
[CID3614365]
Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. [AID2189, Type: screening]
View
46
[SID22405114]
[CID5199378]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
47
[SID22405114]
[CID5199378]
Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. [AID2189, Type: screening]
View
48
[SID24826689]
[CID1614034]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
49
[SID24826744]
[CID3596034]
Epi-absorbance primary biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase [AID1556, Type: screening]
View
50
[SID24826744]
[CID3596034]
Epi-absorbance-based confirmation assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. [AID2189, Type: screening]
View