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BioActivity Data for Target Cellular tumor antigen p53 [gi:269849759]

Filters: All Data » Active      
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BioActivity Outcomes:
Active(1735)
 
 
BioAssay Types:
Confirmatory(697)
 
 
Summary(659)
 
 
Literature(364)
 
 
BioAssay Categories:
Biochemical(371)
 
 
Cell-based(55)
 
 
BioActivity Types:
Potency(1349)
 
 
IC50(279)
 
 
Ki(57)
 
 
Kd(5)
 
 
EC50(2)
 
 
Substance Types:
Chemical(1735)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 60    Data Row: 1735   Total Pages: 87   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID163331640]
[CID67998380]
IC50 0.0009Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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2
[SID160701617]
[CID56965957]
IC50 0.0011Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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3
[SID163317819]
[CID58573876]
IC50 0.0017Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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4
[SID163314357]
[CID60154126]
IC50 0.0018Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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5
[SID144207181]
[CID43116]
Potency-Replicate_1 0.0021qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]
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6
[SID160690851]
[CID56591154]
IC50 0.0022Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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7
[SID144209680]
[CID457193]
Ratio Potency (uM) 0.00227757qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]
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8
[SID144209680]
[CID457193]
Potency-Replicate_1 0.0027qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]
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9
[SID144206639]
[CID148124]
Potency-Replicate_1 0.0027qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]
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10
[SID163335100]
[CID56591137]
IC50 0.0028Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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11
[SID242615354]
[CID58542358]
IC50 0.0028Inhibition of p53 interaction to MDM2 (unknown origin) [AID1118054, Type: Literature]
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12
[SID103489256]
[CID11512578]
Ki 0.003Inhibition of p53 interaction to MDM2 (unknown origin) by fluorescence polarization assay [AID1118052, Type: Literature]
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13
[SID144206334]
[CID148124]
Potency-Replicate_1 0.0042qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]
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14
[SID160701617]
[CID56965957]
IC50 0.0042Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay in presence of 15% human serum [AID706602, Type: Literature]
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15
[SID163317818]
[CID56591324]
IC50 0.0042Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay [AID706601, Type: Literature]
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16
[SID103441496]
[CID11250180]
Kd 0.0048Binding affinity against p53-binding site of Benzodiazepinedione HDM2 [AID238133, Type: Literature]
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17
[SID144205550]
[CID457193]
Potency-Replicate_1 0.0053qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]
View
18
[SID144206334]
[CID148124]
Ratio Potency (uM) 0.00530804qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]
View
19
[SID144206639]
[CID148124]
Ratio Potency (uM) 0.00562256qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]
View
20
[SID144205550]
[CID457193]
Ratio Potency (uM) 0.00630862qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]
View