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M17 leucyl aminopeptidase [Plasmodium falcipa.. [gi:23497510] - Target BioActivity Data
Also known as: M17 leucyl aminopeptidase [Plasmodium falciparum 3D7].
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BioActivity Outcomes:
Active(74)
 
 
BioAssay Types:
Confirmatory(74)
 
 
BioActivity Types:
IC50(74)
 
 
Substance Types:
Chemical(74)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 74   Total Pages: 2   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID125311595]
[CID53384804]
Average PFM17LAP IC50 0.18QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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2
[SID125311594]
[CID53315819]
Average PFM17LAP IC50 0.38QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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3
[SID125311591]
[CID53315818]
Average PFM17LAP IC50 0.41QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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4
[SID93577810]
[CID2466]
Average PFM17LAP IC50 0.41QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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5
[SID125311597]
[CID12814959]
Average PFM17LAP IC50 0.54QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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6
[SID125311588]
[CID14545018]
Average PFM17LAP IC50 0.63QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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7
[SID125311590]
[CID4589721]
Average PFM17LAP IC50 0.74QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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8
[SID104233677]
[CID24689999]
Average PFM17LAP IC50 0.79QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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9
[SID125311608]
[CID53315822]
Average PFM17LAP IC50 0.95QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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10
[SID125311598]
[CID23380591]
Average PFM17LAP IC50 0.98QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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11
[SID131485162]
[CID25922]
Average PFM17LAP IC50 1.39QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]
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12
[SID125311596]
[CID142752]
Average PFM17LAP IC50 1.92QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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13
[SID131485172]
[CID53315831]
Average PFM17LAP IC50 2.16QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]
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14
[SID131485168]
[CID54758533]
Average PFM17LAP IC50 2.26QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]
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15
[SID131485166]
[CID54758532]
Average PFM17LAP IC50 2.27QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3) [AID602309, Type: confirmatory]
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16
[SID125311589]
[CID53384801]
Average PFM17LAP IC50 2.3QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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17
[SID125311593]
[CID53384800]
Average PFM17LAP IC50 2.85QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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18
[SID125311599]
[CID10171341]
Average PFM17LAP IC50 3.3QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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19
[SID125321394]
[CID16002643]
Average PFM17LAP IC50 3.52Counterscreen for inhibitors of PFM1AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602209, Type: confirmatory]
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20
[SID99431869]
[CID3245751]
Average PFM17LAP IC50 3.57Counterscreen for inhibitors of PFM1AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602209, Type: confirmatory]
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21
[SID104233666]
[CID17377721]
Average PFM17LAP IC50 5.13QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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22
[SID104233678]
[CID289794]
Average PFM17LAP IC50 6.11QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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23
[SID125321393]
[CID22430551]
Average PFM17LAP IC50 8.81Counterscreen for inhibitors of PFM1AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602209, Type: confirmatory]
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24
[SID125311601]
[CID23382]
Average PFM17LAP IC50 9.08QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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25
[SID104233676]
[CID2362078]
Average PFM17LAP IC50 10.85QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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26
[SID99343884]
[CID751856]
Average M17 IC50 12.32Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602220, Type: confirmatory]
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27
[SID126490285]
[CID53464134]
Average M17 IC50 14.2Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602220, Type: confirmatory]
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28
[SID104233673]
[CID2385866]
Average PFM17LAP IC50 17.06QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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29
[SID104233672]
[CID2224947]
Average PFM17LAP IC50 17.47QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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30
[SID124767890]
[CID53308676]
Average M17 IC50 18.02Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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31
[SID125311592]
[CID44386193]
Average PFM17LAP IC50 18.03QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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32
[SID104233692]
[CID6098495]
Average M17 IC50 20.01Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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33
[SID125311603]
[CID129232]
Average PFM17LAP IC50 20.6QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
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34
[SID104233699]
[CID17467002]
Average M17 IC50 21.15Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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35
[SID104233703]
[CID49859553]
Average M17 IC50 22.01Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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36
[SID104233697]
[CID17543044]
Average M17 IC50 23.46Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View
37
[SID104233670]
[CID1299166]
Average PFM17LAP IC50 23.6QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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38
[SID104233706]
[CID2412200]
Average M17 IC50 25.31Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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39
[SID104233682]
[CID839551]
Average PFM17LAP IC50 25.61QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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40
[SID124767873]
[CID53308680]
Average M17 IC50 26.58Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View
41
[SID124767874]
[CID53308675]
Average M17 IC50 26.88Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View
42
[SID99343867]
[CID8895585]
Average M17 IC50 29.39Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602220, Type: confirmatory]
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43
[SID104233686]
[CID2815223]
Average M17 IC50 29.4Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View
44
[SID99343875]
[CID17462570]
Average M17 IC50 29.79Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602220, Type: confirmatory]
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45
[SID124767892]
[CID13162550]
Average M17 IC50 30.07Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602220, Type: confirmatory]
View
46
[SID104233688]
[CID5077057]
Average M17 IC50 31.41Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View
47
[SID125311609]
[CID53384798]
Average PFM17LAP IC50 33.21QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (2) [AID602216, Type: confirmatory]
View
48
[SID104233680]
[CID17019804]
Average PFM17LAP IC50 33.52QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]
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49
[SID104233684]
[CID5281416]
Average M17 IC50 35.3Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
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50
[SID104233704]
[CID47034404]
Average M17 IC50 37.05Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]
View