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serine/threonine-protein kinase PLK1 [Homo sa.. [gi:21359873] - Target BioActivity Data
Also known as: serine/threonine-protein kinase PLK1 [Homo sapiens].
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BioActivity Outcomes:
Active(10995)
 
 
BioAssay Types:
Confirmatory(10304)
 
 
Screening(689)
 
 
BioActivity Types:
Potency(10204)
 
 
IC50(79)
 
 
EC50(6)
 
 
Substance Types:
Chemical(10995)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 13    Data Row: 10995   Total Pages: 220   Display: Page     
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#StructureSubstanceCompoundActivityBioAssayLinks
OutcomeTypeValue [μM]
1
[SID47213165]
[CID6484787]
DR IC50 uM 0.022Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
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2
[SID51089839]
[CID74787]
Potency 0.1683qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
3
[SID47213067]
[CID3164070]
DR IC50 uM 0.21Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
4
[SID17407044]
[CID5086667]
DR_IC50uM_Run1 0.22Fluorescence Polarization assay for Plk1: IC50 Dose Response Assay [AID785, Type: confirmatory]
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5
[SID57264557]
[CID1730]
Potency 0.2378qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
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6
[SID47195529]
[CID816729]
Potency 0.2668qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
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7
[SID24791575]
[CID1319707]
Potency 0.2668qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
8
[SID47213026]
[CID6460976]
DR IC50 uM 0.282Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
9
[SID47213156]
[CID322478]
DR IC50 uM 0.295Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
10
[SID17412566]
[CID1494229]
Potency 0.2993qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
11
[SID848038]
[CID650462]
Potency 0.2993qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
12
[SID47213115]
[CID3164062]
DR IC50 uM 0.325Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
13
[SID3715577]
[CID2311082]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
14
[SID11532980]
[CID5455]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
15
[SID14738876]
[CID4386676]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
16
[SID57264275]
[CID1609]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
17
[SID51087989]
[CID4556111]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
18
[SID93576780]
[CID15558347]
Potency 0.3359qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
19
[SID47213134]
[CID3926088]
DR IC50 uM 0.375Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
20
[SID7971429]
[CID1789058]
Potency 0.3769qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
21
[SID7973721]
[CID774975]
Potency 0.3769qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
22
[SID87335845]
[CID10842]
Potency 0.3769qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
23
[SID14744870]
[CID704906]
DR_IC50uM_Run1 0.4Fluorescence Polarization assay for Plk1: IC50 Dose Response Assay [AID785, Type: confirmatory]
View
24
[SID17407044]
[CID5086667]
DR_IC50uM_Run1 0.41PLK1 counterscreening assay for identified PKD inhibitors [AID1383, Type: confirmatory]
View
25
[SID14736712]
[CID5737730]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
26
[SID17505950]
[CID6065961]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
27
[SID22401755]
[CID1335166]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
28
[SID49679273]
[CID4038769]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
29
[SID26671555]
[CID5915936]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
30
[SID24785452]
[CID16188836]
Potency 0.4228qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
31
[SID16952873]
[CID1087088]
DR_IC50uM_Run1 0.46Fluorescence Polarization assay for Plk1: IC50 Dose Response Assay [AID785, Type: confirmatory]
View
32
[SID14731515]
[CID891179]
Potency 0.4744qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
33
[SID17410587]
[CID1486982]
Potency 0.4744qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
34
[SID17506668]
[CID1209375]
Potency 0.4744qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
35
[SID24813372]
[CID5337766]
Potency 0.4744qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
36
[SID47213166]
[CID3164076]
DR IC50 uM 0.488Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
37
[SID47213046]
[CID647501]
DR IC50 uM 0.524Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
38
[SID49673494]
[CID16244880]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
39
[SID26671607]
[CID1325215]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
40
[SID24788895]
[CID1359347]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
41
[SID24797546]
[CID1227531]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
42
[SID24804789]
[CID3155287]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
43
[SID17513297]
[CID917172]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
44
[SID17415359]
[CID2281759]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
45
[SID17385972]
[CID7341556]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
46
[SID14732902]
[CID9550331]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
47
[SID92764367]
[CID5874667]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
48
[SID89852013]
[CID230132]
Potency 0.5323qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]
View
49
[SID47213137]
[CID6484789]
DR IC50 uM 0.552Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View
50
[SID47213136]
[CID4372926]
DR IC50 uM 0.571Concentration Response fluorescence polarization-based assay to test purchased Analogs of Selected Hits from the Polo box domain (PBD) of Plk1 Primary HTS. [AID1083, Type: confirmatory]
View